The Werkself have now gone five games in all competitions without a win. Speaking at the pre-match press conference on Wednesday afternoon, Gerardo Seoane and Robert Andrich were agreed that the team will soon get back to winning ways. The Werkself number eight said: "We'll play together as a team again – I'm sure of that!"
There is great anticipation ahead of the clash with the team currently lying fifth in La Liga: "Matchdays are the best days of the week. We are all in good spirits, everybody in the team and on the staff are competitive types," declared Seoane ahead of the clash on the fourth matchday, which could prove to be very significant in terms of the final positions at the top of Group G.
With seven points each, the Werkself and Real Betis are currently in pole position to progress to the knockout stages. A potential three points in front of the home crowd could give the Black and Reds a cushion in the race for first place, which would guarantee progress to the Round of 16. "We are only focusing on our performance and not making any calculations," Seoane made clear. However, the Swiss coach did say that defending top spot is "obviously the target."

To ensure that happens, the 43-year-old and his staff have analysed recent games in detail and found starting points, "to improve our performances. We are self-critical but continue to be ambitious."
Definitely ruled out for Thursday night are the injured players Timothy Fosu-Mensah, Charles Aránguiz, Julian Baumgartlinger, Patrik Schick, Karim Bellarabi and Mitchel Bakker. It remains to be seen whether Lucas Alario will be able to play. The Argentina striker has suffered muscular problems for several weeks. Against that background, the 29-year-old worked on his own on Wednesday.
Robert Andrich will definitely be in the line-up. The defensive midfielder, signed by Bayer 04 from Union Berlin in the summer, wants to contribute his "personality and aggression" to help get the performances and results for the Werkself back on track. Andrich: "Everyone knows what's happened in the past few weeks. We now have an even closer focus and are, above all, taking care of the basics."
Match information:
Broadcasters: RTL, RTL+ and Werkself Radio
Referee: Anthony Taylor (England)

Bayer 04 Leverkusen continue building the squad for the new season in the Google Pixel Women's Bundesliga. The 25-year-old midfielder Marlene Müller has joined the club from RB Leipzig on a contract to 30 June 2028.
Show more
Bayer 04 are introducing changes to the ticket price structure for the 2026/27 season. In addition to adjusting the ticket prices, the ticket categories will also be reorganised. All season ticket holders have already been informed of the changes by e-mail. The most important information at a glance.
Show more
Ibrahim Maza joined Bayer 04 from Hertha Berlin in the summer of 2025. The youngster from Berlin developed into a difference-maker in his first season with the Werkself. Find out what makes the highly talented player tick in this very personal interview. Among other things, Maza talks about his Algerian-Vietnamese-German home, the role of his family and the importance of Islam for him both in his private life and in football...
Show more
Talking to each other instead of about each other - that was the motto of the ‘Stadiontalk’ on Monday in the BayArena. Representatives from Bayer 04 and other companies, politicians and trainees from the region came together to discuss the career prospects for young people as well as existing challenges and hurdles.
Show more
Bayer 04’s Ibrahim Maza is among the three nominees for the Bundesliga’s 2025/26 Rookie of the Season award. Fans have until 23:59 CEST on Thursday, 7 May to cast their votes in the official Bundesliga app.
Show more