
Three matches, seven points, top spot. That is the almost perfect record for Bayer 04 from the first three games in the current Europa League campaign. The team under head coach Gerardo Seoane are still unbeaten on the European stage – as are Real Betis: The Green and Whites have the same number of points from the first three games but are behind the Werkself due to an inferior goal difference (8:5) compared with the Werkself (7:2).
There are 14 days between the previous and the forthcoming meetings of the two clubs. Striker Borja Iglesias gave Manuel Pellegrini's team the lead from the penalty spot on 75 minutes in the 1-1 draw. Bayer 04 levelled seven minutes later through Robert Andrich. With almost the last kick of the game, Kerem Demirbay had the chance to make it 2-1 but his shot from ten yards was kept out with an impressive reaction save from the Betis goalkeeper Claudio Bravo.
The Andalusian side have played three matches in La Liga since the Europa League clash at the Stadio Benito Villamarin. Immediately after the draw with the Seoane team, Nabil Fekir and Co. overcame Rayo Vallecano with a 3-2 victory in an exciting game at home and that was followed with a convincing 4-1 victory over Valencia in the third home game in succession.
However, Real Betis suffered a defeat on the road last time out: Atlético Madrid were the 3-0 winners last Sunday. Nevertheless, the Green and Whites have moved up three places to fifth place in Spain's top-flight since the last Europa League match against Bayer 04 – their current tally in the league is 21 points from 12 games.
While the Werkself head coach Gerardo Seoane has another player sidelined in Mitchel Bakker (ankle injury), his opposite number Pellegrini has a full squad to choose from for the match at the BayArena.
The Chilean is well known as a fan of rotation: Midfielder Nabil Fekir and striker Borja Iglesias were both on the bench against Atlético. The latter came on as substitute in the closing stages but Fekir did not play.
It is possible the two key players in the Betis attacking game could return to the starting line-up on Thursday. Jonathan Tah and Co. will again have to keep a wary eye on the duo as Fekir and Iglesias have already been involved in eleven goals this season.

The final whistle of the current 2025/26 season marks the end of a unique partnership for Bayer 04 Leverkusen. After more than three decades of collaboration and highly eventful times, the Bundesliga football club and the private brewery Bitburger are going their separate ways.
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Around four months after their bitter exit in the DFB Pokal Round of 16, the Bayer 04 Women are once again away to Hamburger SV. On Monday night (18:00 CEST), the Werkself will not only be looking to pick up important points in the final phase of the Google Pixel Women's Bundesliga at the Volksparkstadion, but also to make amends for their defeat on penalties.
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A simple approach to sport with games, fun and a highlight at the end: Bayer 04 organised a very special training session for 40 participants aged between six and 27 in cooperation with the Football Association of the Middle Rhine (FVM). At the day of action for women and girls with disabilities at the Kurtekotten Performance Centre, many of the participants gained their first experience of football.
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On Saturday, 28 March, the lights will go out again at the BayArena from 20:30 pm to 21:30. As in previous years, Bayer 04 once again take part in the WWF Earth Hour campaign under the motto "We're switching off" as the club wants to set a collective example for more climate and environmental protection together with people, cities and companies around the world.
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