
Three matches, seven points, top spot. That is the almost perfect record for Bayer 04 from the first three games in the current Europa League campaign. The team under head coach Gerardo Seoane are still unbeaten on the European stage – as are Real Betis: The Green and Whites have the same number of points from the first three games but are behind the Werkself due to an inferior goal difference (8:5) compared with the Werkself (7:2).
There are 14 days between the previous and the forthcoming meetings of the two clubs. Striker Borja Iglesias gave Manuel Pellegrini's team the lead from the penalty spot on 75 minutes in the 1-1 draw. Bayer 04 levelled seven minutes later through Robert Andrich. With almost the last kick of the game, Kerem Demirbay had the chance to make it 2-1 but his shot from ten yards was kept out with an impressive reaction save from the Betis goalkeeper Claudio Bravo.
The Andalusian side have played three matches in La Liga since the Europa League clash at the Stadio Benito Villamarin. Immediately after the draw with the Seoane team, Nabil Fekir and Co. overcame Rayo Vallecano with a 3-2 victory in an exciting game at home and that was followed with a convincing 4-1 victory over Valencia in the third home game in succession.
However, Real Betis suffered a defeat on the road last time out: Atlético Madrid were the 3-0 winners last Sunday. Nevertheless, the Green and Whites have moved up three places to fifth place in Spain's top-flight since the last Europa League match against Bayer 04 – their current tally in the league is 21 points from 12 games.
While the Werkself head coach Gerardo Seoane has another player sidelined in Mitchel Bakker (ankle injury), his opposite number Pellegrini has a full squad to choose from for the match at the BayArena.
The Chilean is well known as a fan of rotation: Midfielder Nabil Fekir and striker Borja Iglesias were both on the bench against Atlético. The latter came on as substitute in the closing stages but Fekir did not play.
It is possible the two key players in the Betis attacking game could return to the starting line-up on Thursday. Jonathan Tah and Co. will again have to keep a wary eye on the duo as Fekir and Iglesias have already been involved in eleven goals this season.

Bayer 04 Leverkusen have agreed a loan deal with Bundesliga club Borussia Mönchengladbach for Argentinian striker Alejo Sarco. The 20-year-old joins Mönchengladbach with immediate effect for the rest of the season.
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After their first win on matchday 6 in the UCL league phase, Olympiacos are still in with a good chance of reaching the play-offs in the UEFA Champions League. The 2024 UEFA Conference League winners will be looking to go one better in their home match against Bayer 04 this Tuesday, 20 January (kick-off: 21:00 CET), but their stop scorer is unavailable. The lowdown on our next opponents.
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Panagiotis, known as Panos, Retsos wore the Bayer 04 jersey for three years. Including his loan spells, he was under contract with the Werkself for a total of four and a half years. "It's a very special club for me," said the 27-year-old, who returned to his boyhood club Olympiacos in 2022, in an interview with bayer04.de. The former Leverkusen man is now captain and a first choice for the Werkself's next opponents in the UEFA Champions League. Ahead of the clash on Tuesday night, 20 January (kick-off: 21:00 CET), Retsos talks about his fond memories of his time in Leverkusen and the imminent reunion with some of his former team-mates. He also talks about who brought him to Leverkusen and why he likes getting older.
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Four Bayer 04 players are in action at the 35th edition of the Africa Cup of Nations being played in Morocco from 21 December to 18 January 2026: Eliesse Ben Seghir for the hosts, Edmond Tapsoba with Burkina Faso, Ibrahim Maza for Algeria and Christian Kofane with Cameroon. Updates on the AFCON matches involving Werkself players...
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Bayer 04 Leverkusen will have to manage without goalkeeper Mark Flekken and forward Nathan Tella for the time being.
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