
Three matches, seven points, top spot. That is the almost perfect record for Bayer 04 from the first three games in the current Europa League campaign. The team under head coach Gerardo Seoane are still unbeaten on the European stage – as are Real Betis: The Green and Whites have the same number of points from the first three games but are behind the Werkself due to an inferior goal difference (8:5) compared with the Werkself (7:2).
There are 14 days between the previous and the forthcoming meetings of the two clubs. Striker Borja Iglesias gave Manuel Pellegrini's team the lead from the penalty spot on 75 minutes in the 1-1 draw. Bayer 04 levelled seven minutes later through Robert Andrich. With almost the last kick of the game, Kerem Demirbay had the chance to make it 2-1 but his shot from ten yards was kept out with an impressive reaction save from the Betis goalkeeper Claudio Bravo.
The Andalusian side have played three matches in La Liga since the Europa League clash at the Stadio Benito Villamarin. Immediately after the draw with the Seoane team, Nabil Fekir and Co. overcame Rayo Vallecano with a 3-2 victory in an exciting game at home and that was followed with a convincing 4-1 victory over Valencia in the third home game in succession.
However, Real Betis suffered a defeat on the road last time out: Atlético Madrid were the 3-0 winners last Sunday. Nevertheless, the Green and Whites have moved up three places to fifth place in Spain's top-flight since the last Europa League match against Bayer 04 – their current tally in the league is 21 points from 12 games.
While the Werkself head coach Gerardo Seoane has another player sidelined in Mitchel Bakker (ankle injury), his opposite number Pellegrini has a full squad to choose from for the match at the BayArena.
The Chilean is well known as a fan of rotation: Midfielder Nabil Fekir and striker Borja Iglesias were both on the bench against Atlético. The latter came on as substitute in the closing stages but Fekir did not play.
It is possible the two key players in the Betis attacking game could return to the starting line-up on Thursday. Jonathan Tah and Co. will again have to keep a wary eye on the duo as Fekir and Iglesias have already been involved in eleven goals this season.

Bayer 04 Leverkusen have extended youngster Montrell Culbreath's contract once again. Having only signed a deal with the Bundesliga club until 30 June 2030 in January, still as an U19 player, the attacking midfielder, who's since established himself in the first-team squad, has penned a new contract valid until 30 June 2031. Culbreath joined the Werkself academy in 2023 and made 16 first-team appearances in the 2025/26 season in the Bundesliga, DFB Pokal and Champions League, scoring one goal.
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Ecuador international Piero Hincapie, who moved to Arsenal FC on loan from Bayer 04 Leverkusen for the 2025/26 season, will join the English champions permanently on 1 July 2026.
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The date and kick-off time for Bayer 04’s match in the first round of the 2026/27 DFB Pokal have been confirmed. The Werkself face SV Wehen Wiesbaden on Saturday afternoon, 22 August, at 13:00 CEST. The German Football Association (DFB) announced this today, Wednesday. The Pokal tie against the Hessen state cup winners will be played at the BRITA Arena. Ticket information to follow at a later date.
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Bayer 04 Leverkusen CEO Fernando Carro will lead a club delegation to Brazil from July 2-6 for a program of partner engagement, community activities and football development initiatives across São Paulo and Rio de Janeiro.
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Bayer 04 Leverkusen have extended the contract of promising striker Amy Wrigge on a long-term basis. The 18-year-old Germany U19 international, currently recovering from a torn cruciate in her left knee, has signed a new contract to 30 June 2029.
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