
Three matches, seven points, top spot. That is the almost perfect record for Bayer 04 from the first three games in the current Europa League campaign. The team under head coach Gerardo Seoane are still unbeaten on the European stage – as are Real Betis: The Green and Whites have the same number of points from the first three games but are behind the Werkself due to an inferior goal difference (8:5) compared with the Werkself (7:2).
There are 14 days between the previous and the forthcoming meetings of the two clubs. Striker Borja Iglesias gave Manuel Pellegrini's team the lead from the penalty spot on 75 minutes in the 1-1 draw. Bayer 04 levelled seven minutes later through Robert Andrich. With almost the last kick of the game, Kerem Demirbay had the chance to make it 2-1 but his shot from ten yards was kept out with an impressive reaction save from the Betis goalkeeper Claudio Bravo.
The Andalusian side have played three matches in La Liga since the Europa League clash at the Stadio Benito Villamarin. Immediately after the draw with the Seoane team, Nabil Fekir and Co. overcame Rayo Vallecano with a 3-2 victory in an exciting game at home and that was followed with a convincing 4-1 victory over Valencia in the third home game in succession.
However, Real Betis suffered a defeat on the road last time out: Atlético Madrid were the 3-0 winners last Sunday. Nevertheless, the Green and Whites have moved up three places to fifth place in Spain's top-flight since the last Europa League match against Bayer 04 – their current tally in the league is 21 points from 12 games.
While the Werkself head coach Gerardo Seoane has another player sidelined in Mitchel Bakker (ankle injury), his opposite number Pellegrini has a full squad to choose from for the match at the BayArena.
The Chilean is well known as a fan of rotation: Midfielder Nabil Fekir and striker Borja Iglesias were both on the bench against Atlético. The latter came on as substitute in the closing stages but Fekir did not play.
It is possible the two key players in the Betis attacking game could return to the starting line-up on Thursday. Jonathan Tah and Co. will again have to keep a wary eye on the duo as Fekir and Iglesias have already been involved in eleven goals this season.

Centre-back Melissa Friedrich is set to remain at Bayer 04 for another year. The longest-serving player in the squad, who joined the club in 2016, has extended her contract to 2027.
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Bayer 04 Leverkusen have signed Portugal U21 international Afonso Moreira. The 21-year-old winger joins the club from French top-flight side Olympique Lyon on a contract to 30 June 2031. In France last year, the left-winger made 37 appearances in Ligue 1, the Coupe de France and the UEFA Europa League, scoring a total of eight goals and providing eleven assists.
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A warm welcome to Leverkusen, Afonso Moreira! Bayer 04 have signed the 21-year-old Portuguese player from the top-flight French club Lyon. The left-winger has signed a contract at Leverkusen to 30 June 2031. Bayer04.de takes a closer look at the new signing.
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A new signing for the U19s: Bayer 04 have signed winger Clinton Wilson from Schalke 04. The 18-year-old previously played for Leverkusen youth teams from January to June 2024.
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