
Three matches, seven points, top spot. That is the almost perfect record for Bayer 04 from the first three games in the current Europa League campaign. The team under head coach Gerardo Seoane are still unbeaten on the European stage – as are Real Betis: The Green and Whites have the same number of points from the first three games but are behind the Werkself due to an inferior goal difference (8:5) compared with the Werkself (7:2).
There are 14 days between the previous and the forthcoming meetings of the two clubs. Striker Borja Iglesias gave Manuel Pellegrini's team the lead from the penalty spot on 75 minutes in the 1-1 draw. Bayer 04 levelled seven minutes later through Robert Andrich. With almost the last kick of the game, Kerem Demirbay had the chance to make it 2-1 but his shot from ten yards was kept out with an impressive reaction save from the Betis goalkeeper Claudio Bravo.
The Andalusian side have played three matches in La Liga since the Europa League clash at the Stadio Benito Villamarin. Immediately after the draw with the Seoane team, Nabil Fekir and Co. overcame Rayo Vallecano with a 3-2 victory in an exciting game at home and that was followed with a convincing 4-1 victory over Valencia in the third home game in succession.
However, Real Betis suffered a defeat on the road last time out: Atlético Madrid were the 3-0 winners last Sunday. Nevertheless, the Green and Whites have moved up three places to fifth place in Spain's top-flight since the last Europa League match against Bayer 04 – their current tally in the league is 21 points from 12 games.
While the Werkself head coach Gerardo Seoane has another player sidelined in Mitchel Bakker (ankle injury), his opposite number Pellegrini has a full squad to choose from for the match at the BayArena.
The Chilean is well known as a fan of rotation: Midfielder Nabil Fekir and striker Borja Iglesias were both on the bench against Atlético. The latter came on as substitute in the closing stages but Fekir did not play.
It is possible the two key players in the Betis attacking game could return to the starting line-up on Thursday. Jonathan Tah and Co. will again have to keep a wary eye on the duo as Fekir and Iglesias have already been involved in eleven goals this season.

Werkself-TV shows the highlights of the Bayer 04 women's 0-1 loss against TSG Hoffenheim on the 19th matchday of the Google Pixel Frauen-Bundesliga 2025/26.
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The Bayer 04 Women suffered a setback in the race for third place in the Bundesliga table. Coach Roberto Pätzold's team lost 1-0 at home to direct rivals TSG Hoffenheim on Sunday afternoon, with a penalty after two minutes deciding the match. With 32 points and a game in hand, TSG have moved above the Werkself, who remain on 31 points. There is now a three-week international break before the remaining seven Bundesliga matches.
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Bayer 04 Leverkusen will have to manage without defender Loïc Badé for the time being. The Frenchman suffered a muscle injury in his right thigh in Saturday’s 1-0 Bundesliga defeat at FC Union Berlin. The diagnosis was the result of an MRI scan this Sunday morning.
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It is an expression of solidarity and a tribute to the unique fan culture Under the Cross: Bayer 04 Leverkusen make a special statement with the "50 Years of Fan Clubs" jersey. To mark the founding of the "First Fan Club 1976 Leverkusen", which was followed by many more over the years right up to the present day, the Bundesliga club is commemorating 50 years of passion with this new jersey. Highs and lows, successes celebrated together as well as defeats suffered are manifested in this piece of white fabric, a symbol of unwavering identification with the Werkself.
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