Seoane sees the game against the team sitting sixth in Italy’s Serie A as a very complex endeavour. “Both teams are very attacking but also have a compact defence,” the 43-year-old said. The hosts may be without two strikers in Duvan Zapata and Josip Ilicic, but the Swiss tactician still regards Gian Piero Gasperini’s side as a good and dangerous collective. “They’ve developed well in recent years. It’ll be a tough job, but we can do it.”
Goalkeeper Hradecky has prior experience of facing Gasperini’s team. “I played a friendly here in Bergamo with Frankfurt in 2016 pre-season,” the 32-year-old stated at the press conference. “They were still on their way to the top in Italy at the time. Now they’re a very experienced European team.”
The Leverkusen No.1 is looking forward to an exciting tie against the Italians: “They are extremely aggressive and snappy, but we’ve studied their team well and have to show a mature performance tomorrow.”
Seoane has 19 players available to him for Thursday. The players who haven’t made the journey are goalkeeper Andrey Lunev (ankle), striker Patrik Schick (muscular), winger Karim Bellarabi (muscular), and midfielders Robert Andrich (knee problems), Julian Baumgartlinger (not in the European squad) and Kerem Demirbay (suspended).
Demirbay’s suspension for an accumulation of yellow cards means Seoane has already confirmed that Charles Aranguiz and Exequiel Palacios will be his two holding midfielders. “Both are well capable of being able to make a mark in attack and defence.”

Four Bayer 04 players are in action at the 35th edition of the Africa Cup of Nations being played in Morocco from 21 December to 18 January 2026: Eliesse Ben Seghir for the hosts, Edmond Tapsoba with Burkina Faso, Ibrahim Maza for Algeria and Christian Kofane with Cameroon. Updates on the AFCON matches involving Werkself players...
Show more
Werkself TV shows the highlights of Bayer 04's 3-1 win at RB Leipzig Matchday 15 of the 2025/26 Bundesliga season...
Show more
Bayer 04 ended the year with a 3-1 win away at RB Leipzig and will go into 2026 in third place in the Bundesliga table, leapfrogging their opponents, who had previously not dropped a point at the Red Bull Arena this season. Martin Terrier and Patrik Schick scored to turn around a first-half deficit before Montrell Culbreath rounded things off with a goal on his senior debut deep into added time. Ezequiel Fernández, Axel Tape and Lucas Vázquez also all returned from injury.
Show more
Bayer 04 are away at RB Leipzig for their final fixture of 2025 in the Bundesliga on Saturday (kick-off: 18:30 CET). Here’s all you need to know ahead of the Matchday 15 encounter at the Red Bull Arena.
Show more