Seoane sees the game against the team sitting sixth in Italy’s Serie A as a very complex endeavour. “Both teams are very attacking but also have a compact defence,” the 43-year-old said. The hosts may be without two strikers in Duvan Zapata and Josip Ilicic, but the Swiss tactician still regards Gian Piero Gasperini’s side as a good and dangerous collective. “They’ve developed well in recent years. It’ll be a tough job, but we can do it.”
Goalkeeper Hradecky has prior experience of facing Gasperini’s team. “I played a friendly here in Bergamo with Frankfurt in 2016 pre-season,” the 32-year-old stated at the press conference. “They were still on their way to the top in Italy at the time. Now they’re a very experienced European team.”
The Leverkusen No.1 is looking forward to an exciting tie against the Italians: “They are extremely aggressive and snappy, but we’ve studied their team well and have to show a mature performance tomorrow.”
Seoane has 19 players available to him for Thursday. The players who haven’t made the journey are goalkeeper Andrey Lunev (ankle), striker Patrik Schick (muscular), winger Karim Bellarabi (muscular), and midfielders Robert Andrich (knee problems), Julian Baumgartlinger (not in the European squad) and Kerem Demirbay (suspended).
Demirbay’s suspension for an accumulation of yellow cards means Seoane has already confirmed that Charles Aranguiz and Exequiel Palacios will be his two holding midfielders. “Both are well capable of being able to make a mark in attack and defence.”

An overview of current ticket sales for Bayer 04 home and away matches in the 2026/27 season.
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Three games, three wins: Bayer 04 secured a 2–0 victory at Greek Cup winners OFI Crete with Jonas Hofmann scoring both goals at the Pankritio Stadium, right on the Mediterranean coast (35’, 38’). As a result, the Werkself have temporarily taken over top spot in the table on Matchday 3 of the league phase of the UEFA Europa League.
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'40 Years Across Europe' - and for the first time ever, Bayer 04 are travelling to Greece's biggest island for a European clash. There they'll take on OFI Crete - full name Omilos Filathlon Irakleiou (‘Association of Sports Friends of Heraklion’) - on Matchday 3 of the 2026/27 UEFA Europa League league phase. The meeting with the Greek Cup winners kicks off at 18:45 CEST on Thursday 22 October at the Pankritio. We’ll bring you all the latest updates from the trip here…
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Two games – two wins: Bayer 04 have picked up maximum points from their two matches so far in the league phase of the UEFA Europa League. What's more, of their previous 14 UEL matches, Bayer 04 have lost just one. Away to OFI Crete, Carles Martínez’s side are looking to add another successful performance on the European stage to their string of impressive displays. The Greeks, for their part, have been waiting four matches for a win, but Leverkusen should be on their guard: OFI’s most recent victory came against a German side. Today's matchday news.
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Ahead of Bayer 04's Europa League match away to OFI Crete in Greece, defender Jarell Quansah spoke to Werkself-TV...
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