Seoane sees the game against the team sitting sixth in Italy’s Serie A as a very complex endeavour. “Both teams are very attacking but also have a compact defence,” the 43-year-old said. The hosts may be without two strikers in Duvan Zapata and Josip Ilicic, but the Swiss tactician still regards Gian Piero Gasperini’s side as a good and dangerous collective. “They’ve developed well in recent years. It’ll be a tough job, but we can do it.”
Goalkeeper Hradecky has prior experience of facing Gasperini’s team. “I played a friendly here in Bergamo with Frankfurt in 2016 pre-season,” the 32-year-old stated at the press conference. “They were still on their way to the top in Italy at the time. Now they’re a very experienced European team.”
The Leverkusen No.1 is looking forward to an exciting tie against the Italians: “They are extremely aggressive and snappy, but we’ve studied their team well and have to show a mature performance tomorrow.”
Seoane has 19 players available to him for Thursday. The players who haven’t made the journey are goalkeeper Andrey Lunev (ankle), striker Patrik Schick (muscular), winger Karim Bellarabi (muscular), and midfielders Robert Andrich (knee problems), Julian Baumgartlinger (not in the European squad) and Kerem Demirbay (suspended).
Demirbay’s suspension for an accumulation of yellow cards means Seoane has already confirmed that Charles Aranguiz and Exequiel Palacios will be his two holding midfielders. “Both are well capable of being able to make a mark in attack and defence.”

For the second time in four days, Bayer 04 face Borussia Dortmund this Tuesday evening, 2 December (kick-off: 21:00 CET) - this time in the round of 16 of the DFB Pokal, with more than 7,000 fans supporting the Werkself at Signal Iduna Park. After the recent 2-1 defeat to BVB in the league, several cup stats provide hope of revenge for the Black and Reds. There are several reasons why Bayer 04 recommends getting to the round of 16 clash early, in which VAR will be in use, unlike in the previous rounds. Read on for further information on tonight’s game in our matchday news.
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Just three days on from the Bundesliga meeting in Leverkusen, Bayer 04 now visit Borussia Dortmund in the DFB Pokal on Tuesday (21:00 CET). Ahead of the game at the Signal Iduna Park, head coach Kasper Hjulmand spoke about how to approach this second encounter in 72 hours and a number of developments within the squad.
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Werkself TV shows the highlights of Bayer 04's 2-1 loss to Borussia Dortmund on Matchday 12 of the 2025/26 Bundesliga season...

Bayer 04 were beaten 2-1 at home by Borussia Dortmund on Matchday 12 of the 2025/26 Bundesliga season. Although the Werkself had more of the play in the first half, the visitors went ahead through Aaron Anselmino. Karim Adeyemi doubled their advantage after the hour, but Christian Kofane gave Leverkusen late hope, although ultimately to no avail.
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There won’t just be plenty of excitement on the pitch as Bayer 04 host Borussia Dortmund at the BayArena at 18:30 CET on Saturday. Outside the stadium there will be collection points for food donations to the Leverkusen Foodbank, which will also benefit from the profits of a jersey raffle in the Fanwelt afterwards. There will also be a minute’s silence before kick-off following the passing of long-time Werkself player Dieter Herzog, before two fan clubs are honoured for their decades-long support at half-time and fans receive a talk about Orange Day, the International Day for the Elimination of Violence against Women. Here’s all you need to know ahead of the game in our matchday news.
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