Seoane sees the game against the team sitting sixth in Italy’s Serie A as a very complex endeavour. “Both teams are very attacking but also have a compact defence,” the 43-year-old said. The hosts may be without two strikers in Duvan Zapata and Josip Ilicic, but the Swiss tactician still regards Gian Piero Gasperini’s side as a good and dangerous collective. “They’ve developed well in recent years. It’ll be a tough job, but we can do it.”
Goalkeeper Hradecky has prior experience of facing Gasperini’s team. “I played a friendly here in Bergamo with Frankfurt in 2016 pre-season,” the 32-year-old stated at the press conference. “They were still on their way to the top in Italy at the time. Now they’re a very experienced European team.”
The Leverkusen No.1 is looking forward to an exciting tie against the Italians: “They are extremely aggressive and snappy, but we’ve studied their team well and have to show a mature performance tomorrow.”
Seoane has 19 players available to him for Thursday. The players who haven’t made the journey are goalkeeper Andrey Lunev (ankle), striker Patrik Schick (muscular), winger Karim Bellarabi (muscular), and midfielders Robert Andrich (knee problems), Julian Baumgartlinger (not in the European squad) and Kerem Demirbay (suspended).
Demirbay’s suspension for an accumulation of yellow cards means Seoane has already confirmed that Charles Aranguiz and Exequiel Palacios will be his two holding midfielders. “Both are well capable of being able to make a mark in attack and defence.”

Werkself TV shows highlights of the 2-0 win at Olympiacos in the first leg of the play-offs of the UEFA Champions League 2025/26 league...
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The Werkself beat Olympiacos 2-0 in the 2025/26 UEFA Champions League play-off first leg to claim a crucial victory in the Greek capital. After a focused first-half display with a number of presentable chances, Patrik Schick crowned a textbook counter to hand the Werkself the lead on the hour (60’). The Czech rounded off his brace when he headed in from a corner just 144 seconds later. Bayer 04 maintained their lead with aplomb to achieve a good position for the return leg in Leverkusen.
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Bayer 04 and Olympiacos had only met twice before the current UEFA Champions campaign. After the encounter on Matchday 7 of this season’s league phase, the Werkself travel to face the Greek side for the second time in just four weeks for the knockout play-off first leg. The Black and Reds were dominant for large spells in mid-January but lost 2-0 after missing a number of presentable chances. The Werkself aim to do better on Wednesday night to “seize the chance for revenge,” as managing director sport Simon Rolfes put it. Here’s all you need to know ahead of the game in our matchday news.
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A bitter end to the fifth showdown of the 2025/26 VBL Club Championship as the #B04eSports team failed to take any points in the three remaining matches of the preliminary online round of the fifth and final showdown, missing out on the offline round. They can no longer take points in the overall table. Bayer 04 slipped out on the top eight, so direct participation in the final event for the German Club Championship is no longer possible, with Bayer 04 having to contest the play-offs.
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