Seoane sees the game against the team sitting sixth in Italy’s Serie A as a very complex endeavour. “Both teams are very attacking but also have a compact defence,” the 43-year-old said. The hosts may be without two strikers in Duvan Zapata and Josip Ilicic, but the Swiss tactician still regards Gian Piero Gasperini’s side as a good and dangerous collective. “They’ve developed well in recent years. It’ll be a tough job, but we can do it.”
Goalkeeper Hradecky has prior experience of facing Gasperini’s team. “I played a friendly here in Bergamo with Frankfurt in 2016 pre-season,” the 32-year-old stated at the press conference. “They were still on their way to the top in Italy at the time. Now they’re a very experienced European team.”
The Leverkusen No.1 is looking forward to an exciting tie against the Italians: “They are extremely aggressive and snappy, but we’ve studied their team well and have to show a mature performance tomorrow.”
Seoane has 19 players available to him for Thursday. The players who haven’t made the journey are goalkeeper Andrey Lunev (ankle), striker Patrik Schick (muscular), winger Karim Bellarabi (muscular), and midfielders Robert Andrich (knee problems), Julian Baumgartlinger (not in the European squad) and Kerem Demirbay (suspended).
Demirbay’s suspension for an accumulation of yellow cards means Seoane has already confirmed that Charles Aranguiz and Exequiel Palacios will be his two holding midfielders. “Both are well capable of being able to make a mark in attack and defence.”

The Werkself have reached at least the semi-finals of the DFB Pokal in each of the last three years. The Black-and-Reds would like to make it to the final four of the competition again this season, but to do that they'll need to overcome 1. FC Nürnberg in round two, who travel to the BayArena with momentum following a successful league campaign so far. However, Bayer have a 100 percent record at home in all competitions this season - and have also won six of their last seven home matches in the Pokal. The Matchday News.
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Back at home in the second round of the 2026/27 DFB Pokal, Bayer 04 host FC Nürnberg at the BayArena. The match against the current second-placed side in Bundesliga 2 is on Wednesday 28 October at 20:45 CET. Ahead of the game, head coach Carles Martínez spoke, amongst other things, about his anticipation of the clash in front of a home crowd. The Spaniard also commented on a number of personnel matters, including Ibrahim Maza and Montrell Culbreath, plus the visitors’ coach, Miroslav Klose.
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Now in their third season under head coach Miroslav Klose, FC Nürnberg are among the promotion contenders in Bundesliga 2. On Wednesday 28 October (kick-off: 20:45 CET), the team currently second in the table are away to Bayer 04 in the second round of the DFB Pokal. The lowdown on our next opponents.
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Werkself player Ibrahim Maza has been named in the top ten in the ‘Men’s Young Talent of the Year’ category for 2026. The 20-year-old was at the London Palladium on Monday evening for the 2026 Ballon d’Or awards ceremony. Fernando Carro, Bayer 04 CEO, also attended the ceremony. Lamine Yamal of Barcelona was named the winner in the ‘Men’s Young Talent of the Year’ category.
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Bayer 04 will have to manage without forward Moussa Diaby for their upcoming matches. The 27-year-old Frenchman sustained a thigh injury in the 3-0 defeat against TSG Hoffenheim yesterday afternoon, Sunday 25 October. Diaby is expected to be available again after the international break in November.
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