Seoane sees the game against the team sitting sixth in Italy’s Serie A as a very complex endeavour. “Both teams are very attacking but also have a compact defence,” the 43-year-old said. The hosts may be without two strikers in Duvan Zapata and Josip Ilicic, but the Swiss tactician still regards Gian Piero Gasperini’s side as a good and dangerous collective. “They’ve developed well in recent years. It’ll be a tough job, but we can do it.”
Goalkeeper Hradecky has prior experience of facing Gasperini’s team. “I played a friendly here in Bergamo with Frankfurt in 2016 pre-season,” the 32-year-old stated at the press conference. “They were still on their way to the top in Italy at the time. Now they’re a very experienced European team.”
The Leverkusen No.1 is looking forward to an exciting tie against the Italians: “They are extremely aggressive and snappy, but we’ve studied their team well and have to show a mature performance tomorrow.”
Seoane has 19 players available to him for Thursday. The players who haven’t made the journey are goalkeeper Andrey Lunev (ankle), striker Patrik Schick (muscular), winger Karim Bellarabi (muscular), and midfielders Robert Andrich (knee problems), Julian Baumgartlinger (not in the European squad) and Kerem Demirbay (suspended).
Demirbay’s suspension for an accumulation of yellow cards means Seoane has already confirmed that Charles Aranguiz and Exequiel Palacios will be his two holding midfielders. “Both are well capable of being able to make a mark in attack and defence.”

Four Bayer 04 players are in action at the 35th edition of the Africa Cup of Nations being played in Morocco from 21 December to 18 January 2026: Eliesse Ben Seghir for the hosts, Edmond Tapsoba with Burkina Faso, Ibrahim Maza for Algeria and Christian Kofane with Cameroon. Updates on the AFCON matches involving Werkself players...
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Due to the last-minute postponement of the Bundesliga match between Hamburg and the Werkself on Tuesday, 13 January, Bayer 04 will reimburse the ticket price to all 3,500 fans who had already travelled to Hamburg as a sign of appreciation. The tickets remain valid for the rescheduled match (date not yet set).
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Bayer 04 Leverkusen will have to manage without centre-back Edmond Tapsoba in the coming weeks. The Burkina Faso international returned to the Werkself from the Africa Cup of Nations in Morocco with a muscle injury.
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The Bundesliga fixture between Hamburger SV and Bayer 04 Leverkusen has been postponed at short notice.
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Bayer 04 face Hamburger SV for the first time in almost eight years. Although the Hanseatic city team are often below par on the road, they are regularly in top form in front of their own fans. In particular, 18-year-old shooting star Luka Vuskovic is proving to be a real bonus for Merlin Polzin's team, both in attack and defence. However, that should not scare the Werkself: Not only was the last defeat against the newly promoted team 17 games ago, but Kasper Hjulmand's players are in with a chance of securing their fifth win in six games against HSV. Today’s matchday news.
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