They completed the final pre-match training session on Monday morning as well as the two highly intense sessions the day before: Robert Andrich and Karim Bellarabi have returned from injury – and are available for the return game against Atalanta. In response to a question about Andrich, Gerardo Seoane explained: "Rob contributes a certain factor. His distinctive ball-winning ability and uncompromising approach, including in the air, is good for our game."
Missing for the second leg are Florian Wirtz (torn cruciate), Jeremie Frimpong (ankle ligament injury), Patrik Schick (thigh), goalkeeper Andrey Lunev (rehab after ankle injury) plus Julian Baumgartlinger, who was not named in the Europa League squad due to numbers.
The situation is clear. Given the defeat in the first leg, the hosts at the BayArena have to win to reach the quarter-finals. "That doesn't change our basic approach. We always go onto the pitch to win the game," declared Seoane. "It's an important match for both teams and both have the ambition to go through to the next round."
The Swiss coach said about the team currently seventh in Serie A: "Atalanta are an unflappable team with high intensity and ball-winning ability," said the 43-year-old boss. "We will need a more consistent performance than in the first leg." And as a unit if possible. Due to the long term absence of Wirtz and Frimpong, everybody in the team and on the staff is aware that "we all have to pull even closer together."
Midfield dynamo Exequiel Palacios was also on the top table at the Media Centre at the BayArena on Wednesday. The Argentina international compared the forthcoming knockout game to a final but also emphasised: "It will be an intense dual against a good opponent. Above all, we have to close off their counter-attacks and be very focused in midfield."

Asked about his injured teammates Wirtz and Frimpong, the 23-year-old midfielder said: "Of course, they are key players in our system. But we also have a lot of other good lads with great quality who can make up for their absence," Palacios concluded: "We will give our all for the two of them but also for our fans at the stadium."

The Werkself conceded a goal at home for the first time since the beginning of January 67 minutes into the game against FSV Mainz 05 on Saturday. Jarell Quansah levelled late on for the final score of 1-1 to secure a point and avoid a first home defeat in six games. Bayer 04 were very critical of their performance after the game. The Werkself review.
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Rüdiger Vollborn has been at the club for 40 years, he holds the record number of Bundesliga appearances for the club (401) and is the only Bayer 04 player to have won both the UEFA Cup (1988) and the DFB Pokal (1993). And the Berliner stayed with the Werkself after ending his impressive playing career as he worked as a goalkeeping coach for the following nine years. Vollborn now works under the Bayer Cross as a fan liaison officer and club archivist. Since February 2021, the personalised Black and Red lexicon takes Werkself fans under the heading of 'Rudi recounts...' on a brief trip through the history of Bayer 04 every month…
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From special edition jerseys to fan banners, the home game against Mainz 05 was all about the many Bayer 04 fan clubs. Accordingly, a fitting tribute to the long-standing Werkself supporters was not to be missed during half-time in the Bundesliga match. Fernando Carro, CEO, honoured the up to 50-year anniversaries of six fan clubs in front of the coaches' benches at the BayArena.
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Werkself TV shows the highlights of Bayer 04's 1-1 draw against Mainz 05 on Matchday 24 of the 2025/26 Bundesliga season...

A late goal secured a point for Bayer 04 at home to FSV Mainz 05 in a match that saw the Black and Reds dominant in the second half. Despite lots of possession, the Werkself initially found few gaps and fell behind after 67 minutes when Sheraldo Becker scored in a Mainz counter-attack. In the closing stages, Leverkusen threw everything forward once again and equalised through Jarell Quansah (88').
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