The well-earned point in the Europa League away game at Real Betis (1-1) was followed by last Sunday’s 2-2 draw at FC Köln, which for Gerardo Seoane "felt like a defeat. The team was obviously disappointed and frustrated," added the 42-year-old. But they've shown before, as after the 5-1 defeat against Bayern Munich, "that they can quickly recover and are ready to carry on learning."
The Swiss boss is in good spirits going into the knockout encounter with Karlsruher SC, who are currently eighth in Bundesliga 2. "We want to go through to the next round, have the right attitude on the pitch, show a response and keep on developing," said Seoane at the press conference on Tuesday afternoon.
The stats are in favour of the Black and Reds: Amongst the teams who Bayer 04 have played at least ten times since the Bundesliga was founded, the number of defeats is only better against FC Augsburg (0%) than it is against KSC (14%). The only previous cup clash with the team from South Germany in August 2017 saw the Werkself go through with a 3-0 victory after extra time. Back then, Dominik Kohr, Joel Pohjanpalo and Leon Bailey scored in the pouring rain at the Wildparkstadion.
At that time still in the third division, Karlsruhe developed into a solid second division side last season – above all thanks to head coach and former KSC player Christian Eichner. "They have picked up important away wins. They have a good mix of experienced and young players with good physiques," reported Seoane, who has taken a close look at the opponents with his fellow coaches. “They definitely have weapons, for example impressive set-pieces. But if we produce a good performance then we have a chance of going through to the next round."
Bayer 04 were hit by two setbacks yesterday: Karim Bellarabi suffered a muscle injury in his thigh in Cologne and Patrik Schick a torn ligament in his ankle. The two forwards will probably only be available again after the international break in the middle of November.
Lucas Alario could now get more time on the pitch up front. The Argentina international scored 11 goals in the last Bundesliga campaign. After his start in Seville last week, the 29-year-old has complained of slight muscle problems that meant he was only able to complete parts of full training on Tuesday. "I'm waiting for the feedback from the doctors and physios and then I'll consider the risks. There are still four games to go to the international break and we will always need Lucas given that Schick is ruled out," explained Seoane.
U19 striker Iker Bravo could be in the senior squad for the first time against Karlsruhe. "The idea is in the room," said Seoane who welcomed the Spaniard to the training ground on Tuesday.
The 16-year-old Bravo joined Leverkusen in the summer from the world-renowned La Masia academy at Barcelona. Last weekend, the U19 player netted a brace in the 3-1 win in the U19 Bundesliga match against Fortuna Düsseldorf. That included a notable goal scored an impressive goal scored with an overhead kick.
Match information:
Broadcasters: Sky and Werkself Radio
Referee: Tobias Welz (Wiesbaden)

High spirits and previously untold stories: Around 100 Bayer 04 fans packed the Schwadbud fan pub in the east stand of the BayArena on Thursday evening to be there in person for the first instalment of the new series of events entitled “Rudi lädt ein” (Rudi invites you). They listened intently as long-serving Werkself players Gonzalo Castro and Stefan Kießling chatted with record appearance-maker Rüdiger Vollborn and presenter and stadium announcer Tobias Ufer about their many years together at the club, shared amusing anecdotes and revealed dressing room secrets. Anyone who missed the premiere can already look forward to the second instalment – on 12 May, Rudi will be testing the expert knowledge of Bayer 04 fans during a quiz night.
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The Bundesliga home game against VfL Wolfsburg in the first half of the season was one of those classic ‘days to forget’ for Bayer 04 Women. It started with goalkeeper Charlotte Voll being shown a red card in the first minute of the game, and following a further sending-off, coach Roberto Pätzold's 9-women side ended up losing 5-1 to last season's runners-up. At 18.30 CET on Sunday, they'll have the chance to exact revenge at the AOK Stadium - and pick up valuable points in the race for third place.
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Sofie Zdebel is up for the Goal of the Month award for February on ARD-Sportschau. Fans have until 21 March (19:00 CET) to vote for the Germany U23 international's volley to make it 2-0 in the Bayer 04 Women's derby against FC Köln (2-1).
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Bayer 04 Leverkusen are further expanding their partner network: The feed manufacturer PerNaturam is an official sponsor of the Bayer 04 Womens team. The partnership opens up a wide range of opportunities for the company to position its brand in the Bundesliga environment.
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Do you dream of wearing the Bayer cross on your chest? To play in black and red like your role models Loreen Bender, Cornelia Kramer, Kristin Kögel and co. from the Google Pixel Women's Bundesliga? Then take your chance now! Our female youth teams are once again on the lookout for new talent. That's why Bayer 04 are organising a talent day on 12 April 2026 for the first time this year with trials for female juniors.
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