
Including qualification rounds, the Werkself have advanced the last 13 times when they've won the first leg by a margin of two goals or more. However, West Ham have won their last 11 European games on home soil - seven of them by a two-goal difference, which they'll need again tonight to knock out Bayer 04. The Hammers will certainly draw confidence from the fact they've won three of their last four home encounters with teams from Germany, while the Werkself have only triumphed on one of their last 10 visits to England.
Last year's UEFA Europa Conference League winners must do without a couple of key players tonight, though. Attacker Lucas Paquetá and full-back Emerson are both suspended after being booked in the first leg. It remains to be seen whether top scorer Jarrod Bowen will be fit - the forward missed the first leg due to a back problem.
Last weekend could have hardly turned out more different for both clubs. While the Werkself clinched the first Bundesliga title in the club's history with a 5-0 victory over SV Werder Bremen, West Ham suffered a blow in the Premier League. For the first time in 23 years, the Hammers lost a London derby at home to Fulham, losing 2-0 to the side in 12th place. At full time, manager David Moyes summarised: "I'm really disappointed." The 60-year-old Scot then quickly turned his attention towards today's second leg: "We will get ready for the game on Thursday night now, and hopefully we can respond in the right way.." Goalkeeper Lukas Fabianski, who faced 33 shots on his goal against Leverkusen last week, said after the game against Fulham: "We have a really good record at home in European competitions, so let's see what happens." There's more on the Hammers in our opposition profile.
Spanish referee José María Sánchez has been appointed by UEFA for the clash at the London Stadium. The 40-year-old will be assisted by compatriots Raúl Cabañero and Iñigo Prieto, with Carlos del Cerro Grande as the VAR.

The Bayer 04 Women welcome FC Carl Zeiss Jena to the Ulrich Haberland Stadium on Sunday night in a white retro look - and in a unique Bayer 04 ‘50 Years of Fan Clubs’ special edition jersey. In sporting terms, head coach Roberto Pätzold's team will face the Bundesliga's bottom team at 18:30 CET looking to keep their chances of third place in the table alive with six games left to play.
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Bayer 04 Leverkusen will have to manage without the two strikers in the immediate future. Caroline Kehrer suffered a torn ligament in her right knee and Amy Wrigge tore her cruciate ligament.
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The #B04eSports players now have the next chance to win a trophy. After their elimination in the quarter-finals of the VBL Club Championship Final 2025/26, the German club championship, Marc and Sean Landwehr will compete with seven other teams in the finals of the DFB-ePokal 2026 with prize money totalling €65,000. The "highly motivated" Leverkusen team will face the defending champions FOKUS with well-known influencer Elias ‘EliasN97’ Nerlich in the quarter-finals in Frankfurt on Friday, 20 March (from 18:15 CET). The semi-finals and final will be played on Saturday, 21 March.
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Bayer 04 host Bayern Munich in the semi-finals of the 2025/26 DFB Pokal. The tie will be played on Wednesday, 22 April 2026, at the BayArena with the kick-off at 20:45 CEST. Information on ticket sales.
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Hopes were high but disappointment was evident at the end of the second leg of the Round of 16 of UEFA Champions League 2025/26 with the Werkself losing 2-0 to clinical hosts Arsenal after a 1-1 draw in the first leg. Although this marks the end of the journey in the UCL this term the realisation remains that Bayer 04 are "not as far away as it might feel right now", as head coach Kasper Hjulmand said after the game. The Werkself review.
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