Including qualification rounds, the Werkself have advanced the last 13 times when they've won the first leg by a margin of two goals or more. However, West Ham have won their last 11 European games on home soil - seven of them by a two-goal difference, which they'll need again tonight to knock out Bayer 04. The Hammers will certainly draw confidence from the fact they've won three of their last four home encounters with teams from Germany, while the Werkself have only triumphed on one of their last 10 visits to England.
Last year's UEFA Europa Conference League winners must do without a couple of key players tonight, though. Attacker Lucas Paquetá and full-back Emerson are both suspended after being booked in the first leg. It remains to be seen whether top scorer Jarrod Bowen will be fit - the forward missed the first leg due to a back problem.
Last weekend could have hardly turned out more different for both clubs. While the Werkself clinched the first Bundesliga title in the club's history with a 5-0 victory over SV Werder Bremen, West Ham suffered a blow in the Premier League. For the first time in 23 years, the Hammers lost a London derby at home to Fulham, losing 2-0 to the side in 12th place. At full time, manager David Moyes summarised: "I'm really disappointed." The 60-year-old Scot then quickly turned his attention towards today's second leg: "We will get ready for the game on Thursday night now, and hopefully we can respond in the right way.." Goalkeeper Lukas Fabianski, who faced 33 shots on his goal against Leverkusen last week, said after the game against Fulham: "We have a really good record at home in European competitions, so let's see what happens." There's more on the Hammers in our opposition profile.
Spanish referee José María Sánchez has been appointed by UEFA for the clash at the London Stadium. The 40-year-old will be assisted by compatriots Raúl Cabañero and Iñigo Prieto, with Carlos del Cerro Grande as the VAR.
Bayer 04 Leverkusen will have to manage without centre-back Edmond Tapsoba in the coming weeks. The Burkina Faso international returned to the Werkself from the Africa Cup of Nations in Morocco with a muscle injury.
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The Werkself are away to Hamburg SV at the end of the Hinrunde in the 2025/26 Bundesliga campaign. The match at the newly promoted club is on Tuesday night, 13 January (kick-off: 20:30 CET). Ahead of the first encounter with HSV since 2018, Kasper Hjulmand spoke about the strengths of the opponents, lessons learnt from the home defeat against VfB Stuttgart and provided a squad update.
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In Germany, the temperatures are currently around zero, leaving even professional footballers freezing - but not the Bayer 04 Women. Roberto Pätzold's team have fled the cold to the south and are preparing for the second half of the season at a training camp in the Algarve, almost 2,000 kilometres away from home as the crow flies. The Leverkusen squad landed in Faro on Saturday morning and have already completed the first three training sessions over the weekend.
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It was a disappointing Saturday night. The Werkself lost 4-1 to VfB Stuttgart to start the new year on Bundesliga matchday 16 in 2025/26, a result that left both players and fans disappointed. "We played without any passion," said Alejandro Grimaldo honestly afterwards. Teammate Jarell Quansah was even more self-critical, emphasising: "We were miles off it in the first half. You can't put in a performance like that, especially in front of our own fans and I can only apologise to them, to be honest." Read on for the reaction, facts and stats from the clash with VfB Stuttgart in the Werkself review.
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