Including qualification rounds, the Werkself have advanced the last 13 times when they've won the first leg by a margin of two goals or more. However, West Ham have won their last 11 European games on home soil - seven of them by a two-goal difference, which they'll need again tonight to knock out Bayer 04. The Hammers will certainly draw confidence from the fact they've won three of their last four home encounters with teams from Germany, while the Werkself have only triumphed on one of their last 10 visits to England.
Last year's UEFA Europa Conference League winners must do without a couple of key players tonight, though. Attacker Lucas Paquetá and full-back Emerson are both suspended after being booked in the first leg. It remains to be seen whether top scorer Jarrod Bowen will be fit - the forward missed the first leg due to a back problem.
Last weekend could have hardly turned out more different for both clubs. While the Werkself clinched the first Bundesliga title in the club's history with a 5-0 victory over SV Werder Bremen, West Ham suffered a blow in the Premier League. For the first time in 23 years, the Hammers lost a London derby at home to Fulham, losing 2-0 to the side in 12th place. At full time, manager David Moyes summarised: "I'm really disappointed." The 60-year-old Scot then quickly turned his attention towards today's second leg: "We will get ready for the game on Thursday night now, and hopefully we can respond in the right way.." Goalkeeper Lukas Fabianski, who faced 33 shots on his goal against Leverkusen last week, said after the game against Fulham: "We have a really good record at home in European competitions, so let's see what happens." There's more on the Hammers in our opposition profile.
Spanish referee José María Sánchez has been appointed by UEFA for the clash at the London Stadium. The 40-year-old will be assisted by compatriots Raúl Cabañero and Iñigo Prieto, with Carlos del Cerro Grande as the VAR.
Calling all Bayer 04 fans: The Werkself will play Pisa SC, newly promoted to Serie A, at the BayArena as part of the season opener. The clash with the club from Tuscany is on Tuesday, 5 August with the kick-off at 18:00 CET. Entrance to the stadium with a wide range of entertainment provided is possible from 15:00 CEST. Read on for information on ticket sales for the season opener.
Show moreBayer 04 Leverkusen have signed the 17-year-old forward Dustin Buck. The Germany youth international joins from the youth set-up at FC Augsburg. The technically gifted and fast attacker will strengthen the Werkself U19 squad.
Show moreSeveral Bayer 04 Legends, Bayer executives, club officials, current defender Arthur and, of course, dozens of enthusiastic children turned out on Saturday on the south side of Sao Paulo for the official opening of the Bayer 04 Football Academy, located at Club Bayer on the campus of Bayer Brazil.
Show moreA great night for 'Calle': Bayer 04 new signing Carlotta Wamser helped Germany to an opening win in the Women's Euro in Switzerland with an impressive performance. After coming on as a substitute in the 2-0 victory over Poland in Group C, the winger provided an assist and helped set up the second goal. The 21-year-old earned great praise from her coach and teammates in her first tournament match.
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