Including qualification rounds, the Werkself have advanced the last 13 times when they've won the first leg by a margin of two goals or more. However, West Ham have won their last 11 European games on home soil - seven of them by a two-goal difference, which they'll need again tonight to knock out Bayer 04. The Hammers will certainly draw confidence from the fact they've won three of their last four home encounters with teams from Germany, while the Werkself have only triumphed on one of their last 10 visits to England.
Last year's UEFA Europa Conference League winners must do without a couple of key players tonight, though. Attacker Lucas Paquetá and full-back Emerson are both suspended after being booked in the first leg. It remains to be seen whether top scorer Jarrod Bowen will be fit - the forward missed the first leg due to a back problem.
Last weekend could have hardly turned out more different for both clubs. While the Werkself clinched the first Bundesliga title in the club's history with a 5-0 victory over SV Werder Bremen, West Ham suffered a blow in the Premier League. For the first time in 23 years, the Hammers lost a London derby at home to Fulham, losing 2-0 to the side in 12th place. At full time, manager David Moyes summarised: "I'm really disappointed." The 60-year-old Scot then quickly turned his attention towards today's second leg: "We will get ready for the game on Thursday night now, and hopefully we can respond in the right way.." Goalkeeper Lukas Fabianski, who faced 33 shots on his goal against Leverkusen last week, said after the game against Fulham: "We have a really good record at home in European competitions, so let's see what happens." There's more on the Hammers in our opposition profile.
Spanish referee José María Sánchez has been appointed by UEFA for the clash at the London Stadium. The 40-year-old will be assisted by compatriots Raúl Cabañero and Iñigo Prieto, with Carlos del Cerro Grande as the VAR.
Strengthening the Bayer 04 Leverkusen youth teams: Konstantinos Kotsifakis will join the Werkself from Bundesliga 2 club Hertha Berlin for the 2026/27 season, where he will be a permanent member of the Leverkusen U19 coaching set-up. The German-Greek will also take on an operational role in coaching the Bayer 04 Future Team. The 29-year-old was most recently head coach of the U17s at Hertha Berlin.
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Another award for the Bayer 04 head groundsman and staff: After coming top in the 2021/22, 2022/23 and 2024/25 seasons, the BayArena pitch came second in the Bundesliga Pitch of the Year ranking for the 2025/26 season. VfL Wolfsburg secured the top spot this year, with TSG Hoffenheim in third place.
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Opening opponents, derby weekends, the opponents in the season finale: This information and more will be available to Bayer 04 fans on Thursday, 2 July, when the 2026/27 Bundesliga fixture list is published.
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The next footballing highlight is just around the corner: the 2026 FIFA World Cup, the 23rd edition of the tournament, will be held in the USA, Canada and Mexico and feature 48 teams for the first time. Bayer04.de has all the latest on the Werkself players called up to represent their countries.
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While the majority of the Bayer 04 Women are enjoying their summer break, nine Werkself players will be on duty for their national teams in the coming days. Three of them are competing for a place at the World Cup, while six are involved in two friendlies with the Germany U23 team.
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