
Including qualification rounds, the Werkself have advanced the last 13 times when they've won the first leg by a margin of two goals or more. However, West Ham have won their last 11 European games on home soil - seven of them by a two-goal difference, which they'll need again tonight to knock out Bayer 04. The Hammers will certainly draw confidence from the fact they've won three of their last four home encounters with teams from Germany, while the Werkself have only triumphed on one of their last 10 visits to England.
Last year's UEFA Europa Conference League winners must do without a couple of key players tonight, though. Attacker Lucas Paquetá and full-back Emerson are both suspended after being booked in the first leg. It remains to be seen whether top scorer Jarrod Bowen will be fit - the forward missed the first leg due to a back problem.
Last weekend could have hardly turned out more different for both clubs. While the Werkself clinched the first Bundesliga title in the club's history with a 5-0 victory over SV Werder Bremen, West Ham suffered a blow in the Premier League. For the first time in 23 years, the Hammers lost a London derby at home to Fulham, losing 2-0 to the side in 12th place. At full time, manager David Moyes summarised: "I'm really disappointed." The 60-year-old Scot then quickly turned his attention towards today's second leg: "We will get ready for the game on Thursday night now, and hopefully we can respond in the right way.." Goalkeeper Lukas Fabianski, who faced 33 shots on his goal against Leverkusen last week, said after the game against Fulham: "We have a really good record at home in European competitions, so let's see what happens." There's more on the Hammers in our opposition profile.
Spanish referee José María Sánchez has been appointed by UEFA for the clash at the London Stadium. The 40-year-old will be assisted by compatriots Raúl Cabañero and Iñigo Prieto, with Carlos del Cerro Grande as the VAR.

Will the Bayer 04 U19s take the next step towards their first appearance in the knockout stage of the UEFA Youth League in the away game at Manchester City? Coach Kevin Brok is well aware of this historic opportunity, but he's not about to start worrying about the maths: "We're not concerned with the question of what might be good enough. We invest everything we can and always aim for the maximum. That's our way." The game on this penultimate Matchday 5 of the league phase takes place on Tuesday, 25 November (kick-off: 16:00 CET) at the Manchester City Academy Stadium. Werkself TV will be broadcasting the whole match exclusively for Bayer 04 club members live from 15:50 CET....
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€1,000 and food for a good cause: In keeping with the long-standing cooperation between Bayer 04 and the Tafel Leverkusen e.V. food bank, the U19s are also supporting the charitable organisation in the region. In addition to the generous cheque the team were able to donate to an organisation of their choice as a result of their participation in the UEFA Youth League, coach Kevin Brok's lads donated €500 worth of food - financed by their own team kitty. Ferdinand Pohl, Jesper Schlich and Co. also actively helped to stow the food in the Tafel's premises.
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Bayer 04's impressive run of form has not been affected by the international break: The Werkself followed up their 6-0 victory over Heidenheim with a 3-1 win at VfL Wolfsburg that sees them move up into a Champions League spot in the Bundesliga for the first time this season. In the first half, it was an outstandingly cool and consistent performance by the team under head coach Kasper Hjulmand, who earned a special record at Bayer 04 on Saturday. Find out all about the win at the Volkswagen Arena in the Werkself review.
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Werkself-TV shows the highlights of Bayer 04's 3-1 win at VfL Wolfsburg on the 11th matchday of the Bundesliga 2025/26...
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Bayer 04 delivered impressive proof of their strength at VfL Wolfsburg: The Black and Reds produced a very efficient performance in the 3-1 win, especially in the first half with some clinical finishing. Jonas Hofmann (9'), Edmond Tapsoba (24') and Malik Tillman (33') scored before the break, before Vavro reduced the deficit for the home side after the restart (57').
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