
Including qualification rounds, the Werkself have advanced the last 13 times when they've won the first leg by a margin of two goals or more. However, West Ham have won their last 11 European games on home soil - seven of them by a two-goal difference, which they'll need again tonight to knock out Bayer 04. The Hammers will certainly draw confidence from the fact they've won three of their last four home encounters with teams from Germany, while the Werkself have only triumphed on one of their last 10 visits to England.
Last year's UEFA Europa Conference League winners must do without a couple of key players tonight, though. Attacker Lucas Paquetá and full-back Emerson are both suspended after being booked in the first leg. It remains to be seen whether top scorer Jarrod Bowen will be fit - the forward missed the first leg due to a back problem.
Last weekend could have hardly turned out more different for both clubs. While the Werkself clinched the first Bundesliga title in the club's history with a 5-0 victory over SV Werder Bremen, West Ham suffered a blow in the Premier League. For the first time in 23 years, the Hammers lost a London derby at home to Fulham, losing 2-0 to the side in 12th place. At full time, manager David Moyes summarised: "I'm really disappointed." The 60-year-old Scot then quickly turned his attention towards today's second leg: "We will get ready for the game on Thursday night now, and hopefully we can respond in the right way.." Goalkeeper Lukas Fabianski, who faced 33 shots on his goal against Leverkusen last week, said after the game against Fulham: "We have a really good record at home in European competitions, so let's see what happens." There's more on the Hammers in our opposition profile.
Spanish referee José María Sánchez has been appointed by UEFA for the clash at the London Stadium. The 40-year-old will be assisted by compatriots Raúl Cabañero and Iñigo Prieto, with Carlos del Cerro Grande as the VAR.

Bayer 04 Leverkusen have signed France U17 international Kenan Doganay. The 1.90-metre-tall defensive midfielder, who has Turkish roots, joins Leverkusen from the U19s at French top-flight club Olympique Lyon. He will initially train with and play for the U19 team.
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The Sports Tribunal of the German Football Association (DFB) has fined Bayer 04 Leverkusen €185,000 for spectators setting off pyrotechnic devices during a total of five competitive matches. This relates to four Bundesliga matches and the DFB Pokal semi-final against Bayern Munich. The highest individual fine relates to the away match at FC Köln at the end of April.
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Bayer 04 Leverkusen have extended the contract with U19 goalkeeper Simeon Rapsch. The Germany youth international goalkeeper has signed a long-term contract with the Werkself running to 30 June 2029. The 18-year-old joined Leverkusen from FC Viktoria Köln in the summer of 2024.
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Ken Izekor is leaving Bayer 04 Leverkusen to join third-tier side Alemannia Aachen with immediate effect. The 19-year-old centre-forward joined the club from Alemannia in 2018, and Izekor is now returning to his hometown.
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