
Including qualification rounds, the Werkself have advanced the last 13 times when they've won the first leg by a margin of two goals or more. However, West Ham have won their last 11 European games on home soil - seven of them by a two-goal difference, which they'll need again tonight to knock out Bayer 04. The Hammers will certainly draw confidence from the fact they've won three of their last four home encounters with teams from Germany, while the Werkself have only triumphed on one of their last 10 visits to England.
Last year's UEFA Europa Conference League winners must do without a couple of key players tonight, though. Attacker Lucas Paquetá and full-back Emerson are both suspended after being booked in the first leg. It remains to be seen whether top scorer Jarrod Bowen will be fit - the forward missed the first leg due to a back problem.
Last weekend could have hardly turned out more different for both clubs. While the Werkself clinched the first Bundesliga title in the club's history with a 5-0 victory over SV Werder Bremen, West Ham suffered a blow in the Premier League. For the first time in 23 years, the Hammers lost a London derby at home to Fulham, losing 2-0 to the side in 12th place. At full time, manager David Moyes summarised: "I'm really disappointed." The 60-year-old Scot then quickly turned his attention towards today's second leg: "We will get ready for the game on Thursday night now, and hopefully we can respond in the right way.." Goalkeeper Lukas Fabianski, who faced 33 shots on his goal against Leverkusen last week, said after the game against Fulham: "We have a really good record at home in European competitions, so let's see what happens." There's more on the Hammers in our opposition profile.
Spanish referee José María Sánchez has been appointed by UEFA for the clash at the London Stadium. The 40-year-old will be assisted by compatriots Raúl Cabañero and Iñigo Prieto, with Carlos del Cerro Grande as the VAR.

The Werkself conceded a goal at home for the first time since the beginning of January 67 minutes into the game against FSV Mainz 05 on Saturday. Jarell Quansah levelled late on for the final score of 1-1 to secure a point and avoid a first home defeat in six games. Bayer 04 were very critical of their performance after the game. The Werkself review.
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Rüdiger Vollborn has been at the club for 40 years, he holds the record number of Bundesliga appearances for the club (401) and is the only Bayer 04 player to have won both the UEFA Cup (1988) and the DFB Pokal (1993). And the Berliner stayed with the Werkself after ending his impressive playing career as he worked as a goalkeeping coach for the following nine years. Vollborn now works under the Bayer Cross as a fan liaison officer and club archivist. Since February 2021, the personalised Black and Red lexicon takes Werkself fans under the heading of 'Rudi recounts...' on a brief trip through the history of Bayer 04 every month…
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From special edition jerseys to fan banners, the home game against Mainz 05 was all about the many Bayer 04 fan clubs. Accordingly, a fitting tribute to the long-standing Werkself supporters was not to be missed during half-time in the Bundesliga match. Fernando Carro, CEO, honoured the up to 50-year anniversaries of six fan clubs in front of the coaches' benches at the BayArena.
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Werkself TV shows the highlights of Bayer 04's 1-1 draw against Mainz 05 on Matchday 24 of the 2025/26 Bundesliga season...

A late goal secured a point for Bayer 04 at home to FSV Mainz 05 in a match that saw the Black and Reds dominant in the second half. Despite lots of possession, the Werkself initially found few gaps and fell behind after 67 minutes when Sheraldo Becker scored in a Mainz counter-attack. In the closing stages, Leverkusen threw everything forward once again and equalised through Jarell Quansah (88').
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