
Lukas Hradecky and Co. will find out the next hurdle on the European stage on Friday afternoon 25 February. The draw for the Round of 16 will be made at the UEFA headquarters in Nyon from noon CET. The group winners in the Europa League, alongside Bayer 04 including Bundesliga rivals Eintracht Frankfurt, are drawn in pot one. Pot two has the winners of the play-off round, all the runners-up in the Europa League and teams finishing third in the Champions League groups. In addition to RB Leipzig and Real Betis there are the following seven clubs.
The Werkself could face an opponent from the group stage in the current Europa League campaign in the shape of Real Betis. The runners-up in Group G, who had three points less than the Black and Reds, beat the Russian champions Zenit St Petersburg in the play-offs (3-2, 0-0). The team under head coach Gerardo Seoane drew 1-1 away to the team currently third in La Liga and that was followed by a convincing 4-0 victory at home.
Bayer 04 played Rangers the season before – also in the Round of 16. Leverkusen won 3-1 at Ibrox and that was followed by a 1-0 win at the BayArena. The team currently lying second in Scotland's top flight secured a surprise win against Dortmund in the play-offs (4-2, 2-2).
To be fair, FC Barcelona sounds more like the Champions League rather than the Europa league. However, the top club from Spain only finished third behind Bayern Munich and Benfica in their Champions League group. In the Round of 32 there was a 1-1 draw in the first leg against Napoli that was followed by a 4-2 victory in Italy. The last game between the Werkself and the Catalan side was back on 9 December 2015 – a 1-1 draw at Leverkusen.
Bayer 04 could also draw Sevilla. The record Europa League winners (four titles since 2014) also dropped down from the Champions League. Thanks to a 3-1 in the first leg of the play-offs against Dynamo Zagreb, the 1-0 defeat in the second leg against the top Croatian side did not affect the outcome of the tie.
The Portuguese league is always ranked behind the top five leagues in UEFA's five-year assessment. The following four top clubs are the normal representatives on the European stage: Benfica, Sporting Club, FC Porto and Sporting Braga. The Werkself can face the latter two clubs in the Round of 16. Porto beat Lazio (2-1, 2-2), Braga overcame the surprise team Sheriff Tiraspol (2-0, 3-2 on penalties).
Atalanta are well-known to the majority of football clubs in Europe from previous years. However, the Werkself have never played the club from northern Italy. Atalanta finished third in their Champions League group and then made progress through the Europa League play-off round against Olympiakos (2-1, 3-0).
The Europa League Round of 16 first leg matches will be played on Thursday 10 March with the second legs a week later on 17 March. Bayer 04 are away first.

Today sees Bayer 04 go head-to-head with their next direct rivals in the race for Champions League qualification (kick-off 15:30 CEST). Opponents Stuttgart are currently fifth in the table, level on points with the Werkself but one place below them due to a three-goal inferior goal difference. The Black and Reds' record at Bad Cannstatt tells a clearer story: they've not lost at VfB for over 16 years. One important factor in securing what would be three crucial points away from home is Leverkusen's strength on the counter-attack. Whilst Stuttgart are also extremely dangerous going forward, they will be without their captain. Today’s matchday news.
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Another showdown in the race for the Champions League places takes place in Swabia: on Saturday 9 May (kick-off 15:30 CEST), the Werkself visit VfB Stuttgart, who are only behind on goal difference. In his pre-match press conference, head coach Kasper Hjulmand spoke about confidence, excitement and mentality.
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Reinforcement in attack: Bayer 04 Leverkusen have secured the transfer of striker Maja Sternad from Bundesliga rivals SV Werder Bremen. The 22-year-old has signed a contract until 30 June 2028.
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It's a thrilling situation: as the season draws to a close, Stuttgart and Bayer 04 are heading into the home stretch almost neck and neck. After 32 games, with 17 wins, seven draws and eight defeats each, both teams are on 58 points. Even in terms of goals scored, VfB and the Werkself are level on 66. The Black and Reds have conceded just three fewer goals (43) than their rivals (46), which is why they sit one place behind fourth-placed Leverkusen. This Saturday, 9 May (kick-off: 15.30 CEST), the two teams go head to head at the MHP Arena in Stuttgart. The lowdown on our next opponents.
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