
Lukas Hradecky and Co. will find out the next hurdle on the European stage on Friday afternoon 25 February. The draw for the Round of 16 will be made at the UEFA headquarters in Nyon from noon CET. The group winners in the Europa League, alongside Bayer 04 including Bundesliga rivals Eintracht Frankfurt, are drawn in pot one. Pot two has the winners of the play-off round, all the runners-up in the Europa League and teams finishing third in the Champions League groups. In addition to RB Leipzig and Real Betis there are the following seven clubs.
The Werkself could face an opponent from the group stage in the current Europa League campaign in the shape of Real Betis. The runners-up in Group G, who had three points less than the Black and Reds, beat the Russian champions Zenit St Petersburg in the play-offs (3-2, 0-0). The team under head coach Gerardo Seoane drew 1-1 away to the team currently third in La Liga and that was followed by a convincing 4-0 victory at home.
Bayer 04 played Rangers the season before – also in the Round of 16. Leverkusen won 3-1 at Ibrox and that was followed by a 1-0 win at the BayArena. The team currently lying second in Scotland's top flight secured a surprise win against Dortmund in the play-offs (4-2, 2-2).
To be fair, FC Barcelona sounds more like the Champions League rather than the Europa league. However, the top club from Spain only finished third behind Bayern Munich and Benfica in their Champions League group. In the Round of 32 there was a 1-1 draw in the first leg against Napoli that was followed by a 4-2 victory in Italy. The last game between the Werkself and the Catalan side was back on 9 December 2015 – a 1-1 draw at Leverkusen.
Bayer 04 could also draw Sevilla. The record Europa League winners (four titles since 2014) also dropped down from the Champions League. Thanks to a 3-1 in the first leg of the play-offs against Dynamo Zagreb, the 1-0 defeat in the second leg against the top Croatian side did not affect the outcome of the tie.
The Portuguese league is always ranked behind the top five leagues in UEFA's five-year assessment. The following four top clubs are the normal representatives on the European stage: Benfica, Sporting Club, FC Porto and Sporting Braga. The Werkself can face the latter two clubs in the Round of 16. Porto beat Lazio (2-1, 2-2), Braga overcame the surprise team Sheriff Tiraspol (2-0, 3-2 on penalties).
Atalanta are well-known to the majority of football clubs in Europe from previous years. However, the Werkself have never played the club from northern Italy. Atalanta finished third in their Champions League group and then made progress through the Europa League play-off round against Olympiakos (2-1, 3-0).
The Europa League Round of 16 first leg matches will be played on Thursday 10 March with the second legs a week later on 17 March. Bayer 04 are away first.

At its first general meeting on 5 February 2026 in Frankfurt am Main, the Frauen Bundesliga FBL e.V. made key decisions regarding the future direction of the Women’s Bundesliga. The meeting was based on the results of the negotiations with the German Football Association (DFB) over the past few weeks.
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Werkself-TV shows the highlights of Bayer 04's 3-0 win against FC St. Pauli in the quarter-final of the DFB-Pokal 2025/26...
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Once again in the last four! Bayer 04 put in a mature and, for long stretches, commanding performance to defeat a courageous FC St. Pauli in the quarter-finals of the 2025/26 DFB Pokal to reach the semi-finals of the competition for the third time in a row. Martin Terrier gave Leverkusen the lead on 32 minutes before Patrik Schick made it 2-0 on 63 minutes. Substitute Jonas Hofmann capped off a strong second half for the Werkself with the third goal in added time.
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The German Football League (DFL) has announced the three candidates for the title of Bundesliga Rookie of the Month for January. That includes Werkself player Jarell Quansah. Fans of Bayer 04 can vote for their favourite on the Bundesliga app from now until Thursday, 5 January (23:59 CET).
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As in the past two years, the Werkself are aiming to come out on top in the DFB Pokal quarter-finals on Tuesday night, 3 February (kick-off: 20:45 CET). With eleven home games in a row without defeat against the Kiezkicker, the Black and Reds go into the floodlit match in confident mood. But the Pokal, as is often said, has its own magic and the team from the Millerntor has much more to offer than the current 17th place in the Bundesliga would suggest. After all, Bayer 04 are one of the big German teams the combative Hamburgers have already made life difficult for this season. The matchday news.
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