Lukas Hradecky and Co. will find out the next hurdle on the European stage on Friday afternoon 25 February. The draw for the Round of 16 will be made at the UEFA headquarters in Nyon from noon CET. The group winners in the Europa League, alongside Bayer 04 including Bundesliga rivals Eintracht Frankfurt, are drawn in pot one. Pot two has the winners of the play-off round, all the runners-up in the Europa League and teams finishing third in the Champions League groups. In addition to RB Leipzig and Real Betis there are the following seven clubs.
The Werkself could face an opponent from the group stage in the current Europa League campaign in the shape of Real Betis. The runners-up in Group G, who had three points less than the Black and Reds, beat the Russian champions Zenit St Petersburg in the play-offs (3-2, 0-0). The team under head coach Gerardo Seoane drew 1-1 away to the team currently third in La Liga and that was followed by a convincing 4-0 victory at home.
Bayer 04 played Rangers the season before – also in the Round of 16. Leverkusen won 3-1 at Ibrox and that was followed by a 1-0 win at the BayArena. The team currently lying second in Scotland's top flight secured a surprise win against Dortmund in the play-offs (4-2, 2-2).
To be fair, FC Barcelona sounds more like the Champions League rather than the Europa league. However, the top club from Spain only finished third behind Bayern Munich and Benfica in their Champions League group. In the Round of 32 there was a 1-1 draw in the first leg against Napoli that was followed by a 4-2 victory in Italy. The last game between the Werkself and the Catalan side was back on 9 December 2015 – a 1-1 draw at Leverkusen.
Bayer 04 could also draw Sevilla. The record Europa League winners (four titles since 2014) also dropped down from the Champions League. Thanks to a 3-1 in the first leg of the play-offs against Dynamo Zagreb, the 1-0 defeat in the second leg against the top Croatian side did not affect the outcome of the tie.
The Portuguese league is always ranked behind the top five leagues in UEFA's five-year assessment. The following four top clubs are the normal representatives on the European stage: Benfica, Sporting Club, FC Porto and Sporting Braga. The Werkself can face the latter two clubs in the Round of 16. Porto beat Lazio (2-1, 2-2), Braga overcame the surprise team Sheriff Tiraspol (2-0, 3-2 on penalties).
Atalanta are well-known to the majority of football clubs in Europe from previous years. However, the Werkself have never played the club from northern Italy. Atalanta finished third in their Champions League group and then made progress through the Europa League play-off round against Olympiakos (2-1, 3-0).
The Europa League Round of 16 first leg matches will be played on Thursday 10 March with the second legs a week later on 17 March. Bayer 04 are away first.
Panagiotis, known as Panos, Retsos wore the Bayer 04 jersey for three years. Including his loan spells, he was under contract with the Werkself for a total of four and a half years. "It's a very special club for me," said the 27-year-old, who returned to his boyhood club Olympiacos in 2022, in an interview with bayer04.de. The former Leverkusen man is now captain and a first choice for the Werkself's next opponents in the UEFA Champions League. Ahead of the clash on Tuesday night, 20 January (kick-off: 21:00 CET), Retsos talks about his fond memories of his time in Leverkusen and the imminent reunion with some of his former team-mates. He also talks about who brought him to Leverkusen and why he likes getting older.
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Four Bayer 04 players are in action at the 35th edition of the Africa Cup of Nations being played in Morocco from 21 December to 18 January 2026: Eliesse Ben Seghir for the hosts, Edmond Tapsoba with Burkina Faso, Ibrahim Maza for Algeria and Christian Kofane with Cameroon. Updates on the AFCON matches involving Werkself players...
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Bayer 04 Leverkusen will have to manage without goalkeeper Mark Flekken and forward Nathan Tella for the time being.
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After a week in the Algarve, the Bayer 04 Women returned home on Saturday afternoon. The Werkself had six training sessions, two friendlies and a lot of time together as a team. Roberto Pätzold's team will be back in action in the Google Pixel Women's Bundesliga next Friday for the start of matchday 15.
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"We didn’t make the right decision at the right moments," said captain Robert Andrich after the 1-0 defeat away to TSG Hoffenheim, where Bayer 04 endeavoured to control the game but failed to score. The Werkself also had two enforced substitutions due to injuries. Nevertheless, the coach, captain and debutant Janis Blaswich are positive about the coming weeks. The Werkself review.
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