
Lukas Hradecky and Co. will find out the next hurdle on the European stage on Friday afternoon 25 February. The draw for the Round of 16 will be made at the UEFA headquarters in Nyon from noon CET. The group winners in the Europa League, alongside Bayer 04 including Bundesliga rivals Eintracht Frankfurt, are drawn in pot one. Pot two has the winners of the play-off round, all the runners-up in the Europa League and teams finishing third in the Champions League groups. In addition to RB Leipzig and Real Betis there are the following seven clubs.
The Werkself could face an opponent from the group stage in the current Europa League campaign in the shape of Real Betis. The runners-up in Group G, who had three points less than the Black and Reds, beat the Russian champions Zenit St Petersburg in the play-offs (3-2, 0-0). The team under head coach Gerardo Seoane drew 1-1 away to the team currently third in La Liga and that was followed by a convincing 4-0 victory at home.
Bayer 04 played Rangers the season before – also in the Round of 16. Leverkusen won 3-1 at Ibrox and that was followed by a 1-0 win at the BayArena. The team currently lying second in Scotland's top flight secured a surprise win against Dortmund in the play-offs (4-2, 2-2).
To be fair, FC Barcelona sounds more like the Champions League rather than the Europa league. However, the top club from Spain only finished third behind Bayern Munich and Benfica in their Champions League group. In the Round of 32 there was a 1-1 draw in the first leg against Napoli that was followed by a 4-2 victory in Italy. The last game between the Werkself and the Catalan side was back on 9 December 2015 – a 1-1 draw at Leverkusen.
Bayer 04 could also draw Sevilla. The record Europa League winners (four titles since 2014) also dropped down from the Champions League. Thanks to a 3-1 in the first leg of the play-offs against Dynamo Zagreb, the 1-0 defeat in the second leg against the top Croatian side did not affect the outcome of the tie.
The Portuguese league is always ranked behind the top five leagues in UEFA's five-year assessment. The following four top clubs are the normal representatives on the European stage: Benfica, Sporting Club, FC Porto and Sporting Braga. The Werkself can face the latter two clubs in the Round of 16. Porto beat Lazio (2-1, 2-2), Braga overcame the surprise team Sheriff Tiraspol (2-0, 3-2 on penalties).
Atalanta are well-known to the majority of football clubs in Europe from previous years. However, the Werkself have never played the club from northern Italy. Atalanta finished third in their Champions League group and then made progress through the Europa League play-off round against Olympiakos (2-1, 3-0).
The Europa League Round of 16 first leg matches will be played on Thursday 10 March with the second legs a week later on 17 March. Bayer 04 are away first.

Today, Tuesday 16 December (live on B04eSports Twitch channel from 18:00 CET), the Leverkusen eSports players face the final three matches of the online preliminary round of Showdown Three in the VBL Club Championship 2025/26. In addition to 1. FC Heidenheim 1846 and SV 07 Elversberg, they will play Fortuna Düsseldorf, who are still unbeaten in this third showdown. The lowdown on our next opponents.
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Whether it's the Lions Club, Teens, Bayer 04 Club or Silver Lions - there was a lot going on again this year in all age-specific members' clubs. We look back on an eventful year with numerous events and many exclusive moments with the Werkself. We take a look at what the year 2025 had to offer for the members of the Bayer 04 Club...
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Bayer 04 picked up three points in the last home game of the year with 2-0 win against 1. FC Köln on matchday 14. After a dominant first half with good chances, Martin Terrier, who came on as a substitute in the second half, produced a brilliant scorpion kick to make to 1-0 for the Werkself (66') before captain Robert Andrich rounded off the derby victory with a header six minutes later.
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Bayer 04 host 1. FC Köln at the BayArena in the final home game of 2025 . Today’s match on Saturday, 13 December kicks off at 18:30.30 pm. The Werkself are looking for three points against 1. FC Köln, who are without a win in four games but they do have a shooting star in their ranks up front. The Bayer 04 Volunteering Award will be presented at the derby against the club from Cologne and another fan club will be honoured for many years of loyalty under the Cross. The matchday news.
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