
The Bayer 04 v Lotte tie is a repeat of last season's first-round meeting that the Werkself won 3-0 thanks to goals from Kießling, Calhanoglu and Bender.
In this season's first round Bayer 04 won 2-1 at fifth tier SC Hauenstein. Lotte produced a sensational upset in their opening tie against Bundesliga side Werder Bremen. The team, including former Bayer 04 keeper Benedikt Fernandez, were champions of the Regional League West and thereby achieved promotion to division three. Currently they are ninth in the table with five points from four games.
The second round ties will be played on 25 and 26 October. 16 Bundesliga clubs are still in the competition with only RB Leipzig (6-5 defeat on penalties against Dynamo Dresden) and Werder Bremen (21 defeat away to Sportfreunde Lotte) going out in first round. 13 teams from the second division are in the second round plus the two third division outfits Sportfreunde Lotte and Hallescher FC, and Regional League side FC Astoria Walldorf.


For the second time in four days, Bayer 04 face Borussia Dortmund this Tuesday evening, 2 December (kick-off: 21:00 CET) - this time in the round of 16 of the DFB Pokal, with more than 7,000 fans supporting the Werkself at Signal Iduna Park. After the recent 2-1 defeat to BVB in the league, several cup stats provide hope of revenge for the Black and Reds. There are several reasons why Bayer 04 recommends getting to the round of 16 clash early, in which VAR will be in use, unlike in the previous rounds. Read on for further information on tonight’s game in our matchday news.
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Just three days on from the Bundesliga meeting in Leverkusen, Bayer 04 now visit Borussia Dortmund in the DFB Pokal on Tuesday (21:00 CET). Ahead of the game at the Signal Iduna Park, head coach Kasper Hjulmand spoke about how to approach this second encounter in 72 hours and a number of developments within the squad.
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Werkself TV shows the highlights of Bayer 04's 2-1 loss to Borussia Dortmund on Matchday 12 of the 2025/26 Bundesliga season...

Bayer 04 were beaten 2-1 at home by Borussia Dortmund on Matchday 12 of the 2025/26 Bundesliga season. Although the Werkself had more of the play in the first half, the visitors went ahead through Aaron Anselmino. Karim Adeyemi doubled their advantage after the hour, but Christian Kofane gave Leverkusen late hope, although ultimately to no avail.
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