
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

Bayer 04 Leverkusen have extended Abdoulaye Faye’s contract by a further year to 30 June 2031. During the 2026/27 season, the talented defender will play for Celta Vigo on loan without an option to buy. The 21-year-old Senegalese is set to feature in La Liga and the UEFA Europa League with last season’s sixth-placed side in Spain.
Show more
The Werkself's training camp in Weimarer Land all in one place: in our daily blog you'll find all the insights and updates from the day. The programme on day one (Sunday 2 August) includes a media round with managing director sport Simon Rolfes, free time for the team after the friendly against Rot-Weiss Essen and before an intensive week of training begins, as well as a coffee get-together where CEO Fernando Carro and Rolfes met around 100 fans in the afternoon.
Show more
Bayer 04 Leverkusen have agreed Kerim Alajbegovic’s transfer to Italian record champions Juventus. The club brought the 18-year-old attacking player back to Leverkusen this summer via a buy-back option, following a season at Red Bull Salzburg. Until his move to Austria, the Bosnia international had been playing for Bayer 04’s Under-19s.
Show more
A warm welcome to the Weimarer Land, Bayer 04! The Werkself moved into their accommodation for this year’s training camp on Saturday evening. In Blankenhain, Thuringia, head coach Carles Martínez’s team have a programme of gruelling training sessions – several of which will be open to fans – and team-building activities lined up for the next six days. We’ll be following the Werkself up close and providing you with exclusive insights, quotes, photos and videos from the training camp.
Show more
With 22 days to go until the start of the Bundesliga campaign, the Bayer 04 Women’s team have gained a fresh boost of confidence. In a friendly against Belgian top-flight side KRC Genk on Saturday afternoon, coach Roberto Pätzold’s team secured a 1–0 win. Lobke Loonen (20’) scored the winner for the Black and Reds at the Kurtekotten training centre.
Show more