
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

The Bayer 04 women’s team secured a win in the friendly during the international break. Without a total of eight international players, coach Roberto Pätzold’s team defeated Bundesliga 2 side Borussia Mönchengladbach 3–1 at the Kurtekotten Training Centre, thanks to goals from Lobke Loonen (1’, penalty), Caroline Kehrer (41') and Valentina Mädl (66').
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FSV Mainz 05 went into the international break on the back of an away win at Borussia Mönchengladbach. Currently sixth in the table, the Rheinhessen side – who have been impressive on the road – now aim to continue their good start to the Bundesliga campaign at home when they face the Werkself on Saturday, 10 October (kick-off: 15:30 CEST). In terms of squad selection, Urs Fischer once again has more options at his disposal. Up front, the Mainz coach is likely to continue relying on what is currently the league’s most successful strike partnership. The lowdown on our next opponents.
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Exciting experiences and exclusive insights into the Werkself and the BayArena awaited the young footballers from the BA04 Football Academy Guangzhou in China during their visit to the Rhineland this week. As well as taking part in a joint training session with the Bayer 04 Football Academy, the youngsters marvelled at the Bundesliga club’s stadium during a guided tour. The highlight of the visit was a private press conference with former Bayer 04 striker Stefan Kießling, during which he shared tips from his own career with the young players. On Saturday afternoon, 10 October, the group will round off their visit by supporting the Werkself in the away match in Mainz.
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During the first international break of the 2026/27 season, set to last just under three weeks, nine Bayer 04 first-team players are in action with their respective national teams. Read on for updates on matches featuring Werkself players…
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