
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

Once again, well over 100 Werkself fans were delighted to receive an invitation from the club’s record appearance-maker, Rüdiger Vollborn, to the sold-out Schwadbud at the BayArena. This time, the supporters listened as the club historian provided fascinating, exclusive insights into the period from Bayer 04 being founded in 1904 to the club’s promotion to the Bundesliga in 1979. A journey through time is also planned for the upcoming ‘Rudi lädt ein’ event in early November – this time focusing on the years of the Nazi regime.
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Happy children’s faces at the SSV Lützenkirchen training ground: For the 25th time, the Birkenberg soccer school – organised by SportBund Leverkusen – offered participating youngsters an exciting holiday activity. Meeting a Bayer 04 player has now become a cherished tradition. This time, Ibrahim Maza visited the 150 children and spoke to them about his World Cup experiences, amongst other things. “It’s always lovely to see the children’s enthusiasm for football,” said the 20-year-old, after bringing a sparkle to many eyes with selfies and autographs.
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One day after the successful DFB Pokal first round tie at SV Wehen Wiesbaden (4–0), the mood was understandably really good: Over 400 Bayer 04 supporters gathered on Sunday, 23 August, for the annual fan club meet-up at the BayArena and got in the mood for the new season through direct and informal discussions with Bayer 04 management, head coach Carles Martínez and Werkself players.
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Werkself-TV shows the highlights of the Bayer 04 women's 2-0 win at RB Leipzig on the 1st matchday of the Google Pixel Women's Bundesliga 2026/27.
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