
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

The Leverkusen eSports team played the remaining three of the six matches in the online preliminary round of the fourth showdown in the VBL Club Championship 2025/26. RB Leipzig and SC Freiburg were among the teams with the highest goal threat, including two World Cup participants in their ranks. Although the #B04eSports players were defeated in the matches overall, nine points from the first three games last week were enough for Leverkusen to advance to the offline round in Berlin on 2 February.
Show more
A decisive showdown awaits: The Werkself are aiming to progress to the play-off round of the 2025/26 UEFA Champions League with a home win against Villarreal CF on the eighth and final matchday of the league phase. Ahead of the match on Wednesday, 28 January (kick-off: 21:00 CET), coach Kasper Hjulmand spoke about the importance of the game, the possible return of Edmond Tapsoba and a statement from new signing Jonas Omlin in an exclusive interview with Werkself TV. Lucas Vázquez, for his part, spoke about his role on and off the pitch as well as tomorrow’s opponents, who he often faced in Spain with Real Madrid.
Show more
For Villarreal CF, the match at Bayer 04 on Wednesday, 28 January (kick-off: 21:00 CET), will be their last appearance on the European stage this season. The Spanish side, currently fourth in La Liga, are still without a win in the UEFA Champions League and, with just one point from their seven games so far, have no chance of making the play-offs. The 2021 Europa League winners can therefore play without any pressure at the BayArena and will be looking to bow out of the competition with a good performance. The lowdown on our next opponents.
Show more
Bayer 04 Leverkusen will to have manage without forward Eliesse Ben Seghir. The Morocco international suffered a ligament injury in his left ankle before the AFCON final defeat against Senegal (0-1 a.e.t.).
Show more
The VBL Club Championship 2025/26 continues. Tonight, 27 January (live on Twitch and on the Bayer 04 app from 18:00 CET), the Leverkusen eSports team will play the remaining three matches in the online preliminary round of Showdown Four. They are up against FC Kaiserslautern, SC Freiburg and the current club champions and Showdown Three winners RB Leipzig, with whom Bayer 04, club runners-up and Showdown One winners, shared some memorable moments, especially last year. The lowdown on our next opponents.
Show more