
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

The Werkself training camp in the Weimarer Land all in one place: in our daily blog, you’ll find all the insights and updates from the day. The programme for day two (Monday, 3 August) centres on two training sessions – one in the morning (open to the public) and one in the early evening (behind closed doors) – at the nearby training grounds. In the afternoon, fans can look forward to a big fan meet-up with club legend Paulo Sergio at Schloss Blankenhain.
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Bayer 04 Leverkusen have extended Abdoulaye Faye’s contract by a further year to 30 June 2031. During the 2026/27 season, the talented defender will play for Celta Vigo on loan without an option to buy. The 21-year-old Senegalese is set to feature in La Liga and the UEFA Europa League with last season’s sixth-placed side in Spain.
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The Werkself's training camp in Weimarer Land all in one place: in our daily blog you'll find all the insights and updates from the day. The programme on day one (Sunday 2 August) includes a media round with managing director sport Simon Rolfes, free time for the team after the friendly against Rot-Weiss Essen and before an intensive week of training begins, as well as a coffee get-together where CEO Fernando Carro and Rolfes met around 100 fans in the afternoon.
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Bayer 04 Leverkusen have agreed Kerim Alajbegovic’s transfer to Italian record champions Juventus. The club brought the 18-year-old attacking player back to Leverkusen this summer via a buy-back option, following a season at Red Bull Salzburg. Until his move to Austria, the Bosnia international had been playing for Bayer 04’s Under-19s.
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A warm welcome to the Weimarer Land, Bayer 04! The Werkself moved into their accommodation for this year’s training camp on Saturday evening. In Blankenhain, Thuringia, head coach Carles Martínez’s team have a programme of gruelling training sessions – several of which will be open to fans – and team-building activities lined up for the next six days. We’ll be following the Werkself up close and providing you with exclusive insights, quotes, photos and videos from the training camp.
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