The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin
Bayer 04 Leverkusen have extended the contract with U19 midfielder Jonah Berghoff ahead of schedule. The Germany U18 international has signed professional terms with the club to 30 June 2030.
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With sixth place at the end of the 2025/26 Bundesliga campaign, Bayer 04 ended a season in the top third of the table for the ninth time in a row. While the Werkself were narrowly eliminated in the UEFA Champions League Round of 16 by eventual finalists Arsenal, the Black and Reds reached the semi-finals of the DFB Pokal for the third season in succession. As in previous years, you once again have the opportunity to vote for your Player of the Season. Voting is exclusively for Bayer 04 Club members and only via the Bayer 04 app up to and including 11 June.
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With 46 points in the Google Pixel Women's Bundesliga, the Bayer 04 Women’s team once again broke the previous season's club record and ended up in fifth place - 15 wins is also a record. As in previous years, you now have the opportunity to vote for your Player of the Season. Voting is open exclusively to Bayer 04 Club members and only via the Bayer 04 app by 11 June.
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The guests at the Scala Club in Leverkusen were amazed when host Reiner Calmund suddenly brought the Managing Director of Sport at Bayer 04, Simon Rolfes, and record Werkself appearance maker Rüdiger Vollborn onto the stage. As part of the show "An Evening with Football & Friends", organised by long-serving Bayer 04 managing director and general manager Calmund, the two surprise guests drew plenty of applause - and provided great entertainment in exciting conversations about the past and future.
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