
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

Rüdiger Vollborn has been at the club for 40 years, he holds the record number of Bundesliga appearances for the club (401) and is the only Bayer 04 player to have won both the UEFA Cup (1988) and the DFB Pokal (1993). And the Berliner stayed with the Werkself after ending his impressive playing career working as a goalkeeping coach for the following nine years. Vollborn now works under the Bayer Cross as a fan liaison officer and club archivist. Since February 2021, the personal Black and Red lexicon takes Werkself fans under the heading of 'Rudi recounts...' on a brief trip through the history of Bayer 04 every month…
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Bayer 04 host top French club Marseille at the BayArena on matchday four in the 2026/27 UEFA Europa League group stage. The match kicks off on Thursday 5 November at 21:00 CET. The latest information on ticket sales.
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The BAYER 04 HILFT Day is celebrating an anniversary: for the tenth year running, a large number of employees of the Bundesliga club have been getting involved in a community project in Leverkusen and the surrounding area. Following the refurbishment of the city library last year, this time around some 70 staff members rolled up their sleeves to help out at the Bunker Youth Centre in Leverkusen-Wiesdorf. With the support of the Lebenshilfe workshops in Leverkusen and partner Coca-Cola, a rubber football pitch was laid, a Bayer 04-style lounge was created and other projects were carried out. Werkself players and coaching staff also gave their all.
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Bayer 04 Leverkusen and sponsors club partner NRG24 are continuing their partnership, which has been in place since the summer of 2023. The Bundesliga football club and the energy consultancy firm have extended their successful partnership until 30 June 2027.
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