The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin
Bayer 04 and main sponsor BarmeniaGothaer have shown great commitment to the community as the sale of custom-designed T-shirts for charity in the Fanwelt as part of the “BarmeniaGothaer Brings Joy campaign raised a good €5,000. Bayer 04 matched this sum with an equal contribution. As a result, a total of €10,000 was presented to Edmond Tapsoba for his foundation ahead of the home match against Hamburg. The foundation supports people facing challenging daily circumstances in his home country of Burkina Faso.
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Bayer 04 host Hamburg at the BayArena for the first time since September 2017 on the final day of the 2025/26 Bundesliga season on Saturday (15:30 CEST). HSV are safe in their first campaign back in the top flight after back-to-back wins, but Leverkusen are unbeaten in their last 19 games against promoted teams as they go for the victory they need to have a chance to qualify for the UEFA Champions League. There’s also heavy discounts on food and drinks at the BayArena. Here’s all you need to know ahead of the Matchday 34 fixture in our matchday news.
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As well as previously confirmed departures, Bayer 04 Women will also say goodbye to Vanessa Haim and Shen Menglu before Sunday’s final game of the season at home to Werder Bremen as the pair leave Leverkusen upon the expiration of their contracts.
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The last competitive match of the 2025/26 season takes place at the BayArena on Saturday 16 May (kick-off 15:30 CEST), where Hamburger SV are the visitors. At the pre-match press conference, head coach Kasper Hjulmand discussed the mindset and the approach for the crucial final game against HSV, among other topics.
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