
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

Bayer 04 are away to Croatian champions Dinamo Zagreb on Matchday 5 of the league phase of the 2026/27 UEFA Europa League. The game kicks off on Thursday 26 November at 18:45 CET at the Maksimir Stadium. All the information on ticket sales.
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It wasn’t just on the pitch that there was cause for celebration around the Werkself’s 2–1 home win against SC Freiburg. Plenty of happy faces could be seen near the dugouts at half-time too. Once again, CEO Fernando Carro, alongside former striker and club ambassador Stefan Kießling, paid tribute to eight supporters’ clubs celebrating up to their 30th anniversary on behalf of Bayer 04.
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It was a match that will live long in the memory of everyone involved: The Bayer 04 U19s celebrated their seventh win in seven matches in the DFB Youth League preliminary round – and yet it was a very special victory indeed: in the 4–3 (1–1) win at VfL Bochum 1848, no fewer than five goals came in the final quarter of an hour. As the 90th minute approached, coach Patrick Greveraars’s side found themselves behind, but then fought back in true ‘Laterkusen’ style.
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Under Carles Martínez, the Werkself have so far proved unbeatable at the BayArena. The Spaniard has led his team to victory in all three of their most recent home matches – and, it's worth noting, without conceding a single goal. On Sunday, 18 October (kick-off: 15:30 CEST / live on DAZN and Werkself Radio), current league leaders SC Freiburg will make the trip to Leverkusen, but will be without their top scorer. What's more, the Werkself have won all three of their previous home matches against the Black Forest club. With a goal, Patrik Schick could not only secure a fourth consecutive victory but also set a memorable record. Meanwhile, on what will be the ‘Health Day' at the BayArena, much of the focus will be on physical wellbeing. Today's matchday news.
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Werkself-TV shows the highlights of Bayer 04 Women's 1-1 draw against Eintracht Frankfurt on Matchday 7 of the 2026/27 Google Pixel Women's Bundesliga.
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