The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin
Ten years after retiring as a player, Kristina Sundov is returning to the Bayer 04 Women’s team as assistant coach. The 39-year-old former Croatia international takes over from Remzi Kahraman, who has taken up a new challenge abroad. She has been given a contract to 30 June 2028.
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The training pitches at the BayArena are already buzzing with activity again, even before training officially begins next week. On Monday morning, a small group from the Werkself first-team squad completed a session lasting around an hour. Both new and familiar faces were present.
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One ticket, two matches – and a varied programme of events, including appearances by players from the professional teams: Bayer 04 has come up with something very special for the 2026 season launch on Saturday, 8 August. From morning right through to the evening, Werkself fans can use just one ticket to not only enjoy top-class football from the Bayer 04 teams live, but also to experience unforgettable moments with the whole family through a variety of hands-on activities around the BayArena and the Ulrich Haberland Stadium. The day will also end on a real high note: after both matches, Bayer 04 supporters will have the opportunity to interact directly with the players during joint activities and get to know them from a different angle.
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Issa Traoré is moving from Bayer 04 Leverkusen to Slovakian top-flight side AS Trencin. The club has loaned the centre-back out for one year to this year’s ninth-placed team in the Slovakian league.
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