
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

With 22 days to go until the start of the Bundesliga campaign, the Bayer 04 Women’s team have gained a fresh boost of confidence. In a friendly against Belgian top-flight side KRC Genk on Saturday afternoon, coach Roberto Pätzold’s team secured a 1–0 win. Lobke Loonen (20’) scored the winner for the Black and Reds at the Kurtekotten training centre.
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A successful fourth preseason friendly ahead of the start of the training camp: The Werkself secured a 3-0 victory over Rot-Weiss Essen at the Ulrich Haberland Stadium. The goals in what was a commanding and dominant performance by Leverkusen from the outset were scored by Ibrahim Maza (8'), Patrik Schick from the penalty spot (23’) and, in the second half, Montrell Culbreath with a header (79’). The team set off for their training camp in Blankenhain in the Weimarer Land region after the game.
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Rüdiger Vollborn has been at the club for 40 years, he holds the record number of Bundesliga appearances for the club (401) and is the only Bayer 04 player to have won both the UEFA Cup (1988) and the DFB Pokal (1993). And the Berliner stayed with the Werkself after ending his impressive playing career as he worked as a goalkeeping coach for the following nine years. Vollborn now works under the Bayer Cross as a fan liaison officer and club archivist. Since February 2021, the personal Black and Red lexicon takes Werkself fans under the heading of 'Rudi recounts...' on a brief trip through the history of Bayer 04 every month…
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You have voted – your ‘Team of the Quarter-Century’ has been decided! This historic selection, covering the period from 1 January 2000 to 31 December 2024, features honorary captains, Bundesliga champions, double winners and Champions League finalists. Edmond Tapsoba is the only player from the current Bayer 04 squad to make it into the starting XI, while his team-mate Patrik Schick is on the bench. Simon Rolfes, the current managing director sport, is also in the lie-up. A truly special team that brings together a quarter of a century of Bayer 04 history – and has left a decisive mark on the club.
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Following Patrik Schick, Mark Flekken, Ibrahim Maza and Kerim Alajbegovic earlier this week, the next World Cup participant is back on the training ground in Leverkusen: On Thursday 30 July, Malik Tillman rejoined the squad, completing his first training session under head coach Carles Martínez.
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