The Black and Reds won the last two encounters: In October 1995, there was also a Round of 16 tie that ended in a 4-1 win on penalties after a 4-4 draw after extra time: Bayer 04 secured a 1-0 win in the first round in September 2002. The only time RW Essen came out on top was a 4-1 win in round three in the first DFB Cup meeting in 1981/82.
The Werkself go into Tuesday night's game as the clear favourites – Bayer 04 are in the Round of 16 for the seventh time in the last eight years and have always progressed in the cup against teams from the fourth tier or below – but Essen have already caused cup upsets against two teams this season. "In Bielefeld and Düsseldorf, they have knocked two good opponents out of the competition. RWE are a good team and we have prepared accordingly. At the end of the day, we don't want to be on the end of the next upset so we’ll have to produce a good performance tomorrow," said Peter Bosz at the pre-match press conference.
It could well be match of the season for Essen but "it's also an important game for us," Bosz made clear and he is expecting a defensive opponent. "I think we'll push them back. Essen will be compact in defence and hope to provide a threat in counter-attacks. Therefore, we have to be well organised defensively across the pitch. And, of course, score goals."
Although the results in the league have recently been below par, "we don't need to panic. We analyse what we've done wrong and then work on our game in training," assured the head coach. "Tomorrow we’ll have to take our first chance if possible and then create further goalscoring opportunities and that's how we’ll start."
There will be a late decision on who will be going in search of goals for the Werkself. A number of players suffered knocks in the Bundesliga away game at RB Leipzig. Moussa Diaby, who went off on 59 minutes after a kick on the knee, did not train on Sunday, just like Leon Bailey, who is ruled out due to illness. Only if they can complete the final pre-match training session will they be an option for the squad on Tuesday night. The final session will also be crucial for Sven Bender as well as new signing Jeremie Frimpong who was on the training ground for the first time with the team on Sunday.
In principle, Bosz is open to changes to his team but did emphasise: "We want to win. Therefore, I'll use players who I think can help us most."

After back-to-back away defeats, Bayer 04 Women now face their penultimate home fixture of 2026 as they welcome Hamburg to the Ulrich-Haberland-Stadion on Saturday (14:00 CET) seeking three important points in the Google Pixel Bundesliga.
Show more
Several Werkself players are set to represent their national teams during the final international break of 2026. Here’s an overview of who has been called up and what matches they will face in November. This article will be updated regularly.
Show more
After three consecutive wins in the Europa League, the Werkself suffered their first European defeat of the season against Marseille. In a first half with few chances, the Black and Reds gradually gained more and more control of the game, but were unable to convert that advantage into goals. Miguel Gutiérrez came closest to putting Leverkusen ahead with a shot that hit the crossbar. In the second half, the French side produced clinical finishing, with Amine Gouiri scoring from a counter-attack to make it 1-0 (77’). Right up to the final whistle, the Werkself threw everything forward in search of an equaliser, but were unable to find a way back into the game.
Show more
Bayer 04 are riding a wave of success on the European stage: After three wins from their first three games and as the only team yet to concede a goal, the Werkself sit second in the table in the group stage of the UEFA Europa League. With another three points in their first-ever competitive match against Olympique Marseille on Thursday night, 5 November (kick-off: 21:00 CET), Bayer 04 could leap to the top of the table. Meanwhile, the French side are riding the wave of a winning streak in Ligue 1, but are yet to pick up any points in the Europa League. For one Werkself player, Thursday night will mark a reunion with his former team-mates. Today’s matchday news.
Show more
The Bundesliga has finalised the fixtures for matchdays 12 to 18 of the 2026/27 season. Here is an overview of the dates.
Show more