The Black and Reds won the last two encounters: In October 1995, there was also a Round of 16 tie that ended in a 4-1 win on penalties after a 4-4 draw after extra time: Bayer 04 secured a 1-0 win in the first round in September 2002. The only time RW Essen came out on top was a 4-1 win in round three in the first DFB Cup meeting in 1981/82.
The Werkself go into Tuesday night's game as the clear favourites – Bayer 04 are in the Round of 16 for the seventh time in the last eight years and have always progressed in the cup against teams from the fourth tier or below – but Essen have already caused cup upsets against two teams this season. "In Bielefeld and Düsseldorf, they have knocked two good opponents out of the competition. RWE are a good team and we have prepared accordingly. At the end of the day, we don't want to be on the end of the next upset so we’ll have to produce a good performance tomorrow," said Peter Bosz at the pre-match press conference.
It could well be match of the season for Essen but "it's also an important game for us," Bosz made clear and he is expecting a defensive opponent. "I think we'll push them back. Essen will be compact in defence and hope to provide a threat in counter-attacks. Therefore, we have to be well organised defensively across the pitch. And, of course, score goals."
Although the results in the league have recently been below par, "we don't need to panic. We analyse what we've done wrong and then work on our game in training," assured the head coach. "Tomorrow we’ll have to take our first chance if possible and then create further goalscoring opportunities and that's how we’ll start."
There will be a late decision on who will be going in search of goals for the Werkself. A number of players suffered knocks in the Bundesliga away game at RB Leipzig. Moussa Diaby, who went off on 59 minutes after a kick on the knee, did not train on Sunday, just like Leon Bailey, who is ruled out due to illness. Only if they can complete the final pre-match training session will they be an option for the squad on Tuesday night. The final session will also be crucial for Sven Bender as well as new signing Jeremie Frimpong who was on the training ground for the first time with the team on Sunday.
In principle, Bosz is open to changes to his team but did emphasise: "We want to win. Therefore, I'll use players who I think can help us most."

With sixth place at the end of the 2025/26 Bundesliga campaign, Bayer 04 ended a season in the top third of the table for the ninth time in a row. While the Werkself were narrowly eliminated in the UEFA Champions League Round of 16 by eventual finalists Arsenal, the Black and Reds reached the semi-finals of the DFB Pokal for the third season in succession. As in previous years, you once again have the opportunity to vote for your Player of the Season. Voting is exclusively for Bayer 04 Club members and only via the Bayer 04 app up to and including 11 June.
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With 46 points in the Google Pixel Women's Bundesliga, the Bayer 04 Women’s team once again broke the previous season's club record and ended up in fifth place - 15 wins is also a record. As in previous years, you now have the opportunity to vote for your Player of the Season. Voting is open exclusively to Bayer 04 Club members and only via the Bayer 04 app by 11 June.
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Standing on the pitch where the Werkself players perform - for many Bayer 04 club members, this wish became reality at this year's Members' kickabout. Around 400 active participants of all ages took the opportunity to experience the BayArena from a new and special perspective. And there was also plenty going on in the stands: The event attracted more than 1,000 visitors in total and provided an atmospheric end to the season.
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Lying third in the Bundesliga, the Werkself made a faltering start in 2026 after the winter break, but gradually rediscovered winning ways and, as in the previous campaign, were among the top 16 in Europe and the top four in the DFB Pokal. In the Bundesliga, the Werkself also remained in the race for Champions League qualification right to the end. However, because setbacks repeatedly crept into the Werkself's performances between good displays and crucial games, it was not quite enough to secure a UCL spot in the end. A season with many ups and downs brought sixth place and qualification for the UEFA Europa League. Part II of the review of the 2025/26 season.
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