The Werkself have met Liverpool in four competitive matches to date, all of them in the Champions League. After a 1-0 defeat in the first leg of the 2001/02 quarter-final, Bayer 04 won 4-2 in the second leg to progress. That was the only previous victory over the Reds, for whom it was also their last defeat against German opponents in Europe.
Two further encounters followed in the 2004/05 campaign, with the English side winning both and also going on to win Europe's most prestigious title. Xabi Alonso was a Liverpool player at that time but missed the games against the Werkself through injury. There's an in-depth feature on Alonso's return to his former stomping ground HERE.
In the current Champions League season, the Reds sit second in the league phase table with nine points from three matches. After starting with a 3-1 victory at AC Milan, Arne Slot's side beat Bologna 2-0 at home before a 1-0 win at RB Leipzig. Liverpool have led longer in games than any other team, although Bayer 04 are one of six teams who are yet to trail in a Champions League game this term.
It's been an impressive start to life under Slot. The Dutchman, who moved from Feyenoord in the summer as Jürgen Klopp's successor, is shining on all fronts. The Merseyside club recently reached the quarter-finals of the EFL Cup and are top of the Premier League, where they boast the fewest goals conceded. The attack is firing on all cylinders too: Mohamed Salah has been directly involved in 12 goals in the first 10 matches, Luis Diaz in seven. Not to mention other prominent names like Cody Gakpo, Darwin Nunez or Diogo Jota. The Bayer 04 defence must therefore be prepared for a busy night at Anfield. More on tonight's opponents here.
For all Werkself fans following the game in Liverpool, Bayer 04 partner weloveholidays has summarised the best travel tips for the top attractions in the big city in the English north-west. You can find the article HERE.
For those who can't be there, you can also follow the Werkself's trip in our live blog HERE.
There will be a minute's silence before kick-off in memory of the victims of the flood disaster in eastern Spain. The players of both teams and the referees will also wear black armbands. The region around the city of Valencia was hit by severe flooding last week, killing over 200 people and leaving many more still missing.
UEFA has appointed Danny Makkelie for tonight's fixture. The 41-year-old Dutchman has overseen three competitive matches involving the Werkself to date (two wins, one draw). Makkelie is assisted by compatriots Hessel Steegstra and Jan den Vries on the touchlines, and Rob Dieperink as VAR.
Four Bayer 04 players are in action at the 35th edition of the Africa Cup of Nations being played in Morocco from 21 December to 18 January 2026: Eliesse Ben Seghir for the hosts, Edmond Tapsoba with Burkina Faso, Ibrahim Maza for Algeria and Christian Kofane with Cameroon. Updates on the AFCON matches involving Werkself players...
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Due to the last-minute postponement of the Bundesliga match between Hamburg and the Werkself on Tuesday, 13 January, Bayer 04 will reimburse the ticket price to all 3,500 fans who had already travelled to Hamburg as a sign of appreciation. The tickets remain valid for the rescheduled match (date not yet set).
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Bayer 04 Leverkusen will have to manage without centre-back Edmond Tapsoba in the coming weeks. The Burkina Faso international returned to the Werkself from the Africa Cup of Nations in Morocco with a muscle injury.
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The Bundesliga fixture between Hamburger SV and Bayer 04 Leverkusen has been postponed at short notice.
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Bayer 04 face Hamburger SV for the first time in almost eight years. Although the Hanseatic city team are often below par on the road, they are regularly in top form in front of their own fans. In particular, 18-year-old shooting star Luka Vuskovic is proving to be a real bonus for Merlin Polzin's team, both in attack and defence. However, that should not scare the Werkself: Not only was the last defeat against the newly promoted team 17 games ago, but Kasper Hjulmand's players are in with a chance of securing their fifth win in six games against HSV. Today’s matchday news.
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