
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

With seven points, Mainz 05 are currently joint seventh, level on points with sixth-placed Bayer 04. In today’s head-to-head clash (kick-off: 15:30 CEST), the Werkself must be particularly wary of the clinical Mainz strike duo. For Leverkusen fans who have left it to the last minute, there are still a few tickets available from the matchday ticket office. Those following the Black and Reds from home, on the other hand, have a choice: RTL is broadcasting the match on free-to-air TV, and Werkself Radio is also offering the expert commentary of former Bayer 04 player Falko Götz. Today’s matchday news.
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Back from the international break: On Saturday 10 October (kick-off: 15:30 CEST), the Werkself are away to Mainz 05. Ahead of the clash at the MEWA ARENA against the side currently sixth in the table, head coach Carles Martínez spoke, amongst other things, about the team’s work during the extended international break. The Spaniard also commented, when asked, on a number of squad matters, including Ibrahim Maza.
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FSV Mainz 05 went into the international break on the back of an away win at Borussia Mönchengladbach. Currently sixth in the table, the Rheinhessen side – who have been impressive on the road – now aim to continue their good start to the Bundesliga campaign at home when they face the Werkself on Saturday, 10 October (kick-off: 15:30 CEST). In terms of squad selection, Urs Fischer once again has more options at his disposal. Up front, the Mainz coach is likely to continue relying on what is currently the league’s most successful strike partnership. The lowdown on our next opponents.
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Thomas Eichin has been working for Bayer 04 for six years – as Director of Professional Teams since July 2023 – and has contributed to the successful development of our club in many areas. Today, Friday 9 October, Freiburg-born Eichin is celebrating his 60th birthday. We wish him a very happy birthday.
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Together with his family, friends and close associates, Bayer 04 Leverkusen bid farewell to Peter Hermann. The club’s long-serving assistant manager passed away on 19 September following a serious illness. Today, Thursday 8 October, Bayer 04 held an event attended by around 200 invited guests to commemorate Peter Hermann’s legacy. Representatives from the DFB and the other professional clubs where Hermann worked paid their respects to him at the BayArena.
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