
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

Plenty going on both on and off the pitch: The Bayer 04 fan support team has organised a number of highlights for fans visiting the Werkself 2026/27 summer training camp in Blankenhain, in the Weimarer Land region. Registration for the events is now open. All the details at a glance.
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The Bayer 04 Leverkusen Women’s team and s2-Software are continuing their long-term partnership: The Werkself and the provider of pre-owned Microsoft licences have extended their contract by two years to 2028. This means s2-Software will remain the Bayer 04 sleeve sponsor for all matches in the Google Pixel Women’s Bundesliga.
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BIOGENA is the new performance partner for the Bayer 04 Leverkusen Women’s team. Under a partnership initially set to run for three years, the club and the leading Austrian micronutrient company are pooling their expertise in the areas of health, fitness and top-level performance.
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100 children from the Bayer 04 Football Academy had the chance to gain exclusive insights: As part of the summer camp, the young footballers headed inside the BayArena at midday on Tuesday, 21 July, where they were due to meet Werkself keepers Janis Blaswich and Simeon Rapsch in the press conference room. The two players took plenty of time to answer every question from the inquisitive audience – whether it was about their own careers or their first impressions of the new head coach. Finally, there was even time left to sign autographs for the young fans.
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Following the cancellation of Bayer 04’s scheduled friendly against Carl Zeiss Jena on 1 August, the Werkself have now found a new opponent for the same day and will host Rot-Weiss Essen of the 3. Liga at the Ulrich-Haberland-Stadion. Kick-off is at 11:00 CEST and tickets are available now.
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