
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

Will the Bayer 04 U19s take the next step towards their first appearance in the knockout stage of the UEFA Youth League in the away game at Manchester City? Coach Kevin Brok is well aware of this historic opportunity, but he's not about to start worrying about the maths: "We're not concerned with the question of what might be good enough. We invest everything we can and always aim for the maximum. That's our way." The game on this penultimate Matchday 5 of the league phase takes place on Tuesday, 25 November (kick-off: 16:00 CET) at the Manchester City Academy Stadium. Werkself TV will be broadcasting the whole match exclusively for Bayer 04 club members live from 15:50 CET....
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€1,000 and food for a good cause: In keeping with the long-standing cooperation between Bayer 04 and the Tafel Leverkusen e.V. food bank, the U19s are also supporting the charitable organisation in the region. In addition to the generous cheque the team were able to donate to an organisation of their choice as a result of their participation in the UEFA Youth League, coach Kevin Brok's lads donated €500 worth of food - financed by their own team kitty. Ferdinand Pohl, Jesper Schlich and Co. also actively helped to stow the food in the Tafel's premises.
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Werkself-TV shows the highlights of Bayer 04's 3-1 win at VfL Wolfsburg on the 11th matchday of the Bundesliga 2025/26...
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Werkself-TV shows the highlights of the Bayer 04 women's 0-1 loss against SGS Essen on the 11th matchday of the Google Pixel Frauen-Bundesliga 2025/26.
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An unfortunate end to a hard-fought game from Bayer 04's point of view: The Bayer 04 Women worked hard against bottom-of-the-table SGS Essen, but lacked penetration in attack for long periods of the game. The goal scored by Essen's Natasha Kowalski (58'), that saw the otherwise flawless goalkeeper Anne Moll unfortunately slip, was enough to inflict a third consecutive defeat on Roberto Pätzold's team.
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