The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin
Bayer 04 are away to FC Copenhagen on the first matchday of the league phase in the 2025/26 UEFA Champions League. The game against the Danish record champions is on Thursday, 18 September (kick-off: 18:45 CEST) at the Parken Stadium. Ahead of the match, here are some travel tips from Bayer 04 partner weloveholidays for all travelling fans of the Werkself.
Show moreWerkself-TV shows the highlights of the Bayer 04 women's 3-2 win against 1. FC Union Berlin on the 2nd matchday of the Google Pixel Frauen-Bundesliga 2025/26...
Show moreThe successor to Sergi Runge as head coach of the Bayer 04 U19 team has been decided. Following the Spaniard's appointment to Kasper Hjulmand's first team coaching staff, the current U17 head coach Kevin Brok (photo) will be responsible for the U19s until the end of the season. As a result, Benjamin Adam will also move up a year and will now coach the U17s instead of the U16s, also until the end of the season. The structure of the coaching and support staff will remain unchanged.
Show moreThe Werkself are away to Mainz 05 on matchday 7 of the 2025/26 Bundesliga season. The game at the MEWA ARENA is on Saturday, 18 October, with the kick-off at 15.30 CEST. Read on for information on ticket sales.
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