The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin
Bayer 04 Leverkusen will to have manage without forward Eliesse Ben Seghir. The Morocco international suffered a ligament injury in his left ankle before the AFCON final defeat against Senegal (0-1 a.e.t.).
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The VBL Club Championship 2025/26 continues. Tonight, 27 January (live on Twitch and on the Bayer 04 app from 18:00 CET), the Leverkusen eSports team will play the remaining three matches in the online preliminary round of Showdown Four. They are up against FC Kaiserslautern, SC Freiburg and the current club champions and Showdown Three winners RB Leipzig, with whom Bayer 04, club runners-up and Showdown One winners, shared some memorable moments, especially last year. The lowdown on our next opponents.
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Bayer 04 Leverkusen have signed Swiss goalkeeper Jonas Omlin from Borussia Mönchengladbach. The 32-year-old joins the Werkself from the Lower Rhine Bundesliga club on loan to the end of the current season. This is the reaction of Bayer 04 to the injury to first choice keeper Mark Flekken, who faces a long spell on the sidelines.
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Welcome to Leverkusen, Jonas Omlin. Bayer 04 have signed the 32-year-old goalkeeper on loan from Bundesliga side Borussia Mönchengladbach until the end of the season. Managing director sport Simon Rolfes described the Swiss shot stopper, signed by the Werkself in reaction to the long-term absence of first choice keeper Mark Flekken, as an "internationally experienced keeper." Bayer04.de takes a closer look at the new signing, who will wear the number 18 jersey.
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Lucas Vázquez was the hero in Saturday's 1-0 home win against Werder Bremen, when the Spaniard scored his first Bundesliga goal to secure an important victory for Leverkusen. The 34-year-old right-sided recently met up with the Werkself magazine for an interview in the Düsseldorf restaurant Casa Galicia after the first few months of settling in to his new home in Germany. Over tapas, the five-time Champions League winner, who left Real Madrid in the summer after 18 years to continue his career at Bayer 04, spoke about his career to date, the new challenge in Leverkusen and the importance of family - and he paid a big compliment to the fans of his new club.
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