
The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin

Former Werkself star Michael Ballack, who won the German Footballer of the Year award in 2002 while playing in Leverkusen, celebrates his 50th birthday on Saturday. Bayer 04 sends him its best wishes!
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Attention Werkself fans: In addition to tickets for the floodlit home match against Werder Bremen, tickets are now also available for the Bayer 04 women’s team’s two subsequent fixtures against Eintracht Frankfurt and Hamburger SV at the Ulrich Haberland Stadium. Both matches in the Google Pixel Women’s Bundesliga will take place at family-friendly kick-off times on Saturday afternoons. Here is the latest information on matchday ticket sales.
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Guéla Doué’s first 30 minutes in a Bayer 04 shirt during the draw away at Augsburg have definitely made the summer signing eager for more. The 23-year-old may have had to bide his time following his move from Strasbourg due to a muscular injury, but he’s been able to get a good taste of the BayArena atmosphere while watching from the stands in the home wins over Celje and RB Leipzig, as the Ivory Coast international explained in a chat with media representatives. “The fans’ enthusiasm and passion are incredible,” said Doué, looking forward to what lies ahead. The defender also spoke about his plans for a comeback, his teammates and his younger brother Désiré.
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Bayer 04 Leverkusen welcomes a new official member to the Sponsors’ Club at the start of the 2026/27 campaign. KKV Kabelverlegung GmbH & Co. KG is expanding its existing partnership and will, with immediate effect, act as a supporter of the Bundesliga club at the second-highest partner level, just below the premium tier. As an official partner in the Sponsors’ Club, KKV will now enjoy significantly enhanced visibility during Werkself matches at the BayArena. The new contract is initially valid until 30 June 2028.
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Bayer 04 Leverkusen has extended the existing partnership agreement with EDO Personalservice GmbH and, at the same time, expanded its collaboration with the Cologne-based company. The official partner in the Business Club has been upgraded within Bayer 04’s partner network. The revised and enhanced support for the club has initially been agreed for two years, running until 30 June 2028.
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