The second round will be played on Tuesday 26 October and Wednesday 27 October. Exact fixture details will be announced in due course. Then the start of ticket sales will be released.
Sporting director Simon Rolfes: "KSC are an interesting opponent, a team with ambition in the second division. We are at home and we want to live up to our role as favourites."
Head coach Gerardo Seoane: "I'm looking forward to this game as the cup competition is something special. Of course, we face certain expectations as the higher placed club. But we also have them ourselves. The next round is the clear target and that's how we want to approach the game against Karlsruhe from the start."
While the Werkself and KSC have played each other 34 times in the Bundesliga the two sides have only meant once before in the DFB Cup. That was a first-round tie at the Wildpakstadion on 11 August 2017. KSC had just been relegated from the second division but performed well and took the game to extra time with a certain amount of luck. Bayer 04 were then able to turn their visual superiority into goals on the scoreboard. Dominik Kohr, Joel Pohjanpalo and Leon Bailey netted the goals in a 3-0 win. The Werkself went through to the second round and only went out of the cup competition at the semi-final stage against Bayern Munich.
Preußen Münster vs Hertha BSC
Waldhof Mannheim vs Union Berlin
VfL Osnabrück vs SC Freiburg
SV Babelsberg vs RB Leipzig
1860 München vs Schalke 04
Hannover 96 vs Fortuna Düsseldorf
VfL Bochum vs FC Augsburg
Borussia Mönchengladbach vs Bayern Munich
Dynamo Dresden vs FC St. Pauli
TSG Hoffenheim vs Holstein Kiel
Jahn Regensburg vs Hansa Rostock
FC Nürnberg vs Hamburg SV
FSV Mainz 05 vs Arminia Bielefeld
VfB Stuttgart vs FC Köln
Borussia Dortmund vs FC Ingolstadt
Round of 16: 18 and 19 January 2022
Quarter-finals: 1 and 2 March
Semi-finals: 19 and 20 April
Final: 21 May in Berlin
Standing on the pitch where the Werkself players perform - for many Bayer 04 club members, this wish became reality at this year's Members' kickabout. Around 400 active participants of all ages took the opportunity to experience the BayArena from a new and special perspective. And there was also plenty going on in the stands: The event attracted more than 1,000 visitors in total and provided an atmospheric end to the season.
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Lying third in the Bundesliga, the Werkself made a faltering start in 2026 after the winter break, but gradually rediscovered winning ways and, as in the previous campaign, were among the top 16 in Europe and the top four in the DFB Pokal. In the Bundesliga, the Werkself also remained in the race for Champions League qualification right to the end. However, because setbacks repeatedly crept into the Werkself's performances between good displays and crucial games, it was not quite enough to secure a UCL spot in the end. A season with many ups and downs brought sixth place and qualification for the UEFA Europa League. Part II of the review of the 2025/26 season.
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Rogier Meijer is leaving Bayer 04 Leverkusen and returning to his native Netherlands: The 44-year-old will take over at Eredivisie club Sparta Rotterdam on 1 July. Meijer has been part of the Werkself coaching set-up since the start of the 2025/26 season - first as assistant coach to Erik ten Hag, then on Kasper Hjulmand's staff.
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Following the final match of the 2025/26 season, the prevailing feeling was naturally one of disappointment after missing out on qualification for the Champions League. The Werkself finished the Bundesliga in sixth place, meaning they'll start the 2026/27 campaign in the Europa League. "But to talk negatively about everything now because of that would be wrong," stressed captain Robert Andrich following the final game, knowing that the past year at Bayer 04 was marked, more than almost any other, by the start of a new era and the courage to change – and in particular, the belief in a positive direction. Everyone was aware this process would need time. The first part of the 2025/26 season review.
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