
The league campaign kicks off on the weekend of 27-29 August; the Werkself Women are at home to VfL Wolfsburg (10-12 December) at the end of the first half of the season. The final match ahead of New Year and the opening fixture of the first half of the season will be played on 17-19 December. After an eight-week winter break, the FLYERALARM Women’s Bundesliga restarts on the first weekend in February (4-6). The last matchday of the season is on 15 May.
The second round of the DFB Cup, when Bayer 04 and the other Bundesliga clubs join the competition, is planned for 25/26 September.
Matchday 1, 27-29.8. (Return game : 17-19.12.)
FC Carl Zeiss Jena vs Bayer 04
Matchday 2, 3-5.9. (Return game: 4-6.2.2022)
Bayer 04 vs SGS Essen
Matchday 3, 10-12.9. (Return game: 11-13.2.2022)
Bayer 04 vs Turbine Potsdam
Matchday 4, 1-3.10. (Return game: 4-6.3.2022)
Werder Bremen vs Bayer 04
Matchday 5, 8.-10.10. (Return game: 11.-13.03.2022)
Bayer 04 vs SC Sand
Matchday 6, 15-17.10. (Return game: 18.-20.03.2022)
SC Freiburg vs Bayer 04
Matchday 7, 5-7.11. (Return game: 25-27.3.2022)
Bayer 04 vs FC Köln
Matchday 8, 12.-14.11 (Return game: 1-3.4.2022)
TSG 1899 Hoffenheim vs Bayer 04
Matchday 9, 19-21.11. (Return game: 22-24.4.2022)
Bayer 04 vs Eintracht Frankfurt
Matchday 10, 03.-05.12. (Return game: 6-8.5.2022)
FC Bayern Munich vs Bayer 04
Matchday 11, 10.-12.12. (Return game: 15.5.2022)
Bayer 04 vs VfL Wolfsburg

Goalkeeper Anne Moll will leave Bayer 04 Leverkusen at the end of the season. The 21-year-old will join second-tier club VfL Bochum 1848 when her contract expires on 30 June.
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Ahead of the conclusion to the 2025/26 season with the Werkself and the World Cup with Argentina, Bayer 04 midfielder Exequiel Palacios answered questions from journalists from the Latin America region. In a digital media round, the 27-year-old, who's been in Leverkusen since 2020, spoke about the "great development potential" in the current Werkself squad as well as his World Cup ambitions with the Albiceleste, among other things.
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Full-back Julia Mickenhagen is leaving Bayer 04 Leverkusen at the end of the season to join Bundesliga newcomers VfB Stuttgart. The 21-year-old’s contract with the club expires on 30 June.
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Werkself-TV shows the highlights of the Bayer 04 women's 3-1 win at RB Leipzig on the 25th matchday of the Google Pixel Frauen-Bundesliga 2025/26.
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