This will be the fourth DFB Cup tie between the two Bundesliga rivals. The previous meeting was in the quarter-finals of the 2019/20 season with the Werkself Women winning 3-2 after extra time.
Bayer 04 beat second division RB Leipzig 3-1 in the second round to qualify for the Round of 16; TSG went through to the next round with a 5-0 win at Regional League FC Würzburger Kickers.
The Round of 16 ties will be played on 30 and 31 October. Sky will broadcast a top game in each round.
Turbine Potsdam vs FC Köln
SC Freiburg vs VfL Wolfsburg
Bayer 04 vs TSG Hoffenheim
Bayern Munich vs Eintracht Frankfurt
Werder Bremen vs SC Sand
Karlsruher SC vs FC Carl Zeiss Jena
Sportfreunde Siegen vs SV Henstedt-Ulzburg
Hamburg SV vs SGS Essen
Bayer 04 Leverkusen have signed France U17 international Kenan Doganay. The 1.90-metre-tall defensive midfielder, who has Turkish roots, joins Leverkusen from the U19s at French top-flight club Olympique Lyon. He will initially train with and play for the U19 team.
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The Sports Tribunal of the German Football Association (DFB) has fined Bayer 04 Leverkusen €185,000 for spectators setting off pyrotechnic devices during a total of five competitive matches. This relates to four Bundesliga matches and the DFB Pokal semi-final against Bayern Munich. The highest individual fine relates to the away match at FC Köln at the end of April.
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Bayer 04 Leverkusen have extended the contract with U19 goalkeeper Simeon Rapsch. The Germany youth international goalkeeper has signed a long-term contract with the Werkself running to 30 June 2029. The 18-year-old joined Leverkusen from FC Viktoria Köln in the summer of 2024.
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Ken Izekor is leaving Bayer 04 Leverkusen to join third-tier side Alemannia Aachen with immediate effect. The 19-year-old centre-forward joined the club from Alemannia in 2018, and Izekor is now returning to his hometown.
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