This will be the fourth DFB Cup tie between the two Bundesliga rivals. The previous meeting was in the quarter-finals of the 2019/20 season with the Werkself Women winning 3-2 after extra time.
Bayer 04 beat second division RB Leipzig 3-1 in the second round to qualify for the Round of 16; TSG went through to the next round with a 5-0 win at Regional League FC Würzburger Kickers.
The Round of 16 ties will be played on 30 and 31 October. Sky will broadcast a top game in each round.
Turbine Potsdam vs FC Köln
SC Freiburg vs VfL Wolfsburg
Bayer 04 vs TSG Hoffenheim
Bayern Munich vs Eintracht Frankfurt
Werder Bremen vs SC Sand
Karlsruher SC vs FC Carl Zeiss Jena
Sportfreunde Siegen vs SV Henstedt-Ulzburg
Hamburg SV vs SGS Essen
After eight years in the youth set-up at Bayer 04 Leverkusen, Benjamin Adam is leaving the club. The 35-year-old, who most recently coached the Leverkusen U17s, will take charge of the Hansa Rostock U19 team next season.
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Bayer 04 have signed 16-year-old defensive midfielder Kennet Eichhorn from Hertha Berlin. The Germany U17 international is joining the Werkself from the Berlin Bundesliga 2 club on a long-term contract. Eichhorn made 19 appearances for the Hertha Berlin first team last season, scoring two goals.
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Welcome to Leverkusen, Kennet Eichhorn. Bayer 04 have signed the 16-year-old midfielder from Hertha Berlin. Read on to find out more about our new signing.
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There was a successful end to the women's internationals with Werkself players Carlotta Wamser and Cornelia Kramer qualifying for the 2027 World Cup finals in Brazil. A third Leverkusen player is still in with a chance of joining them. The Germany U23 players also experienced success in their last two international friendlies of the season.
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