This will be the fourth DFB Cup tie between the two Bundesliga rivals. The previous meeting was in the quarter-finals of the 2019/20 season with the Werkself Women winning 3-2 after extra time.
Bayer 04 beat second division RB Leipzig 3-1 in the second round to qualify for the Round of 16; TSG went through to the next round with a 5-0 win at Regional League FC Würzburger Kickers.
The Round of 16 ties will be played on 30 and 31 October. Sky will broadcast a top game in each round.
Turbine Potsdam vs FC Köln
SC Freiburg vs VfL Wolfsburg
Bayer 04 vs TSG Hoffenheim
Bayern Munich vs Eintracht Frankfurt
Werder Bremen vs SC Sand
Karlsruher SC vs FC Carl Zeiss Jena
Sportfreunde Siegen vs SV Henstedt-Ulzburg
Hamburg SV vs SGS Essen
Werkself player Montrell Culbreath and Bayer 04 loanee Francis Onyeka are part of Germany's final squad for the U19 European Championships this summer. The tournament is in Wales from 24 June to 12 July.
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Bayer 04 are away to third-division club SV Wehen Wiesbaden in the first round of the 2026/27 DFB Pokal. That was the outcome of the draw on Saturday night, 6 June, at the German Football Museum in Dortmund. The Werkself first round tie will be played between 21 and 24 August. The exact date has yet to be finalised.
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Carles Martìnez is raring to go. The 42-year-old speaks in his first interview in Leverkusen about the club's development to date and how he wants to build on it. He describes his previous work in France, Kuwait, Qatar and his native Barcelona, his experience in developing young players, and the key steps between now and the start of pre-season training.
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New Bayer 04 head coach Carles Martínez has arrived in Leverkusen! At midday on Friday, the 42-year-old spoke in a press conference at the BayArena about his philosophy and his aims. Managing director sport Simon Rolfes also discussed the reasons for appointing the former Toulouse boss.
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