
The first home game against RB Leipzig is on a Saturday afternoon as are the games for the Werkself on the following matchdays three and four at newly-promoted VfB Stuttgart and at home to FSV Mainz 05.
After the first group match in the Europa League (20/21 October) the team led by head coach Peter Bosz have a Monday night game against FC Augsburg; after the second and third group matches (27/28 October and 3/4 November) the Werkself play on Sundays at Freiburg and at home against Borussia Mönchengladbach. The clash with newly promoted Arminia Bielefeld is on a Saturday.
Matchday 1: Sunday, 20.09., 18.00 CET
VfL Wolfsburg v Bayer 04
Matchday 2: Saturday, 26.09., 15.30 CET
Bayer 04 – RB Leipzig
Matchday 3: Saturday, 03.10., 15.30 CET
VfB Stuttgart v Bayer 04
Matchday 4: Saturday, 17.10., 15.30 CET
FSV Mainz 05 v Bayer 04
Matchday 5: Monday, 26.10., 20.30 CET
Bayer 04 v FC Augsburg
Matchday 6: Sunday, 01.11., 15.30 CET
SC Freiburg v Bayer 04
Matchday 7: Sunday, 08.11., 18.00 CET
Bayer 04 v Borussia Mönchengladbach
Matchday 8: Saturday, 21.11., 15.30 CET
Arminia Bielefeld v Bayer 04

Werkself-TV shows the highlights of the Bayer 04 women's 1-3 loss against Werder Bremen on the 26th matchday of the Google Pixel Frauen-Bundesliga 2025/26.
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Bayer 04 Leverkusen have agreed a conract extension with home-grown talent Sofie Zdebel by a further year ahead of schedule. The 21-year-old Germany U23 international will stay at the club until 30 June 2028.
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Bayer 04 could only manage a 1-1 draw at home to Hamburg in the final game of the 2025/26 Bundesliga season as they finish in sixth place and qualify for the UEFA Europa League. Patrik Schick missed a first-half penalty before Fabio Vieira put the visitors ahead on the hour. Jarell Quansah’s deflected header in the 79th minute earned a point to finish the campaign.
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Jonas Omlin was given an official send-off ahead of the final Bundesliga game of the season at home to Hamburg. The 32-year-old Swiss goalkeeper joined the Werkself on loan for the second half of the campaign from Borussia Mönchengladbach in the winter.
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