The new Bayer 04 head coach Gerardo Seoane will welcome his squad for the start of the pre-season on 5 July. And now it is clear which opponents Charles Aránguiz and Co. will open the 2021/22 black and red season against: Last season's surprise team Union Berlin. That is followed by matches against Borussia Mönchengladbach, FC Augsburg and Borussia Dortmund.
The first meeting with champions Bayern Munich is on matchday eight in the middle of October and is followed a week later by the derby at FC Köln (22 to 24 October).
Bayer 04 finish 2021 with an away game at SC Freiburg just before Christmas. After the three-week break, league action returns on the weekend of 7 to 9 January with the home game against Union Berlin. The last match of the season for the Werkself is against SC Freiburg on 14 May.
Matchday 1, 14/15.8. (Return game: 7-9.1.22)
Union Berlin vs Bayer 04
Matchday 2, 20-22.8. (Return game: 14-16.1.22)
Bayer 04 vs Borussia Mönchengladbach
Matchday 3, 27.-29.8. (Return game: 21-23.1.22)
FC Augsburg vs Bayer 04
Matchday 4, 11/12.9. (Return game: 4-6.2.22)
Bayer 04 vs Borussia Dortmund
Matchday 5, 17-19.9. (Return game: 11-13.2.22)
VfB Stuttgart vs Bayer 04
Matchday 6, 24-26.9. (Return game: 18.-20.2.22)
Bayer 04 vs FSV Mainz 05
Matchday 7, 1-3.10. (Return game: 25-27.2.22)
Arminia Bielefeld vs Bayer 04
Matchday 8, 15-17.10. (Return game: 4-6.3.22)
Bayer 04 vs Bayern Munich
Matchday 9, 22-24.10. (Return game: 11-13.3.22)
FC Köln vs Bayer 04
Matchday 10, 29-31.10. (Return game: 18-20.3.22)
Bayer 04 vs VfL Wolfsburg
Matchday 11, 5-7.11. (Return game: 1-3.4.22)
Hertha BSC vs Bayer 04
Matchday 12, 19-21.11. (Return game: 8-10.4.22)
Bayer 04 vs VfL Bochum
Matchday 13, 26-28.11. (Return game: 16/17.4.22)
RB Leipzig vs Bayer 04
Matchday 14, 3-5.12. (Return game: 22-24.4.22)
Bayer 04 vs SpVgg Greuther Fürth
Matchday 15, 10-12.12. (Return game: 29/30.4.22)
Eintracht Frankfurt vs Bayer 04
Matchday 16, 14/15.12. (Return game: 6-8.5.22)
Bayer 04 vs TSG Hoffenheim
Matchday 17, 17-19.12. (Return game: 14.5.22)
SC Freiburg vs Bayer 04
>>>>> Click here for the Bayer 04 digital fixture list <<<<<
Strengthening the Bayer 04 Leverkusen youth teams: Konstantinos Kotsifakis will join the Werkself from Bundesliga 2 club Hertha Berlin for the 2026/27 season, where he will be a permanent member of the Leverkusen U19 coaching set-up. The German-Greek will also take on an operational role in coaching the Bayer 04 Future Team. The 29-year-old was most recently head coach of the U17s at Hertha Berlin.
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Opening opponents, derby weekends, the opponents in the season finale: This information and more will be available to Bayer 04 fans on Thursday, 2 July, when the 2026/27 Bundesliga fixture list is published.
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The next footballing highlight is just around the corner: the 2026 FIFA World Cup, the 23rd edition of the tournament, will be held in the USA, Canada and Mexico and feature 48 teams for the first time. Bayer04.de has all the latest on the Werkself players called up to represent their countries.
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While the majority of the Bayer 04 Women are enjoying their summer break, nine Werkself players will be on duty for their national teams in the coming days. Three of them are competing for a place at the World Cup, while six are involved in two friendlies with the Germany U23 team.
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